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Miniaturized Ir/IrO_x wireless pH sensor for bio-sensing system

文献类型： 会议论文

第一作者： Chindanai RATANAPORNCHAROEN

作者： Chindanai RATANAPORNCHAROEN 1 ; Miyuki TABATA 1 ; Noboru ISHIHARA 2 ; Kasuya MASU 2 ; Mana SRIYUDTHSAK 3 ; Tatsuro GODA 1 ; Akira MATSUMOTO 1 ; Yuji MIYAHARA 1 ;

作者机构： 1.Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University

2.FIRST, Institute of Innovative Research, Tokyo Institute of Technology

3.Faculty of Engineering, Chulalongkorn University

会议名称： センサ·マイクロマシンと応用システム シンポジウム

主办单位：

页码： 669-670

摘要： The pH sensing plays an important role for several kinds of the detection of bio-organism and enzymatic reaction. The pH sensors have been widely used for biosensing devices such as DNA sequencers, enzyme biosensor, and immune sensors. Although major types of pH detection methods are well-known: namely pH imaging using fluorescence probe, optical fiber based-pH sensing, and potentiometric pH detection, the potentiometric measurement has some advantages due to its simplicity of fabrication and operation, compared with other kinds of detection techniques. Furthermore, it is obvious that the pH sensor combined with the wireless communication module becomes more useful for practical applications. In this research, we fabricated the needle-type Ir/IrO_x pH sensor with a diameter of 300 μm by oxidizing Ir wire at 750℃ for 4 hours. In order to develop the prototype of the wireless communication module for biosensor application, we fabricated the measurement circuit and combined with wireless data communication module as shown in figure 1 and 2. Subsequently, we tested the sensitivity of the pH sensor and compatibility between the module and the pH sensor. Firstly, the potentiometric response of Ir/IrO_x pH sensor was monitored in 7 different pH solutions from pH 3 to pH 9 as shown in figure 3a. Then the pH sensitivity was calculated from the pH-potential relationship and compared with the simplified Nernstian equation at T = 25℃; E = -59.2 * pH + E_0, E: electrode potential, E_0: standard potential.

分类号： TP212-53

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