您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

QRS Width and T-Peak to T-End Interval Are Prolonged in Preadolescents with Severe Intrauterine Growth Restriction at Birth when Compared to Controls

文献类型： 会议论文

第一作者： Freddy L Bueno–Palomeque

作者： Freddy L Bueno–Palomeque 1 ; Konstantinos A Mountris 2 ; Nuria Ortigosa 3 ; Raquel Bailón 4 ; Bart Bijnens 5 ; Fàtima Crispi 6 ; Esther Pueyo 4 ; Ana Mincholé 4 ; Pablo Laguna 4 ;

作者机构： 1.BSICoS Group, I3A, IIS Aragón, Universidad de Zaragoza, Zaragoza, Spain|CIBER en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain|GIHEA, Universidad Politécnica Salesiana, Cuenca, Ecuador

2.Mechanical Engineering, University College London, London, United Kingdom

3.I.U. Matemática Pura y Aplicada, Universitat Politècnica de València, Valencia, Spain

4.BSICoS Group, I3A, IIS Aragón, Universidad de Zaragoza, Zaragoza, Spain|CIBER en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Zaragoza, Spain

5.ICREA, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

6.BCNatal- Barcelona Center for Maternal-Fetal and Neonatal Medicine, Hospital Sant Joan de Déu and Hospital Clínic, University of Barcelona, Barcelona, Spain

关键词： Arrhythmia;Computational modeling;Electrocardiography;Biomarkers;Cardiology;Dispersion;Thickness measurement

会议名称： Computing in Cardiology Conference

主办单位：

页码： 1-4

摘要： The aim of this study is to assess how increased globularity and wall thickness resulting from intrauterine growth restriction (IUGR) in preadolescents affects the QRS width, T-peak to T-end and QT intervals, all biomarkers associated with susceptibility to ventricular arrhythmia. 12-lead ECG from 33 subjects who had severe IUGR and 60 control subjects were studied. Spatial principal component analysis was applied to the multilead ECG to emphasize the QRS complex and T-wave, followed by QRS detection and T-wave delineation to derive QRS width, $T_{pe}, QT$ intervals and the ratio $T_{pe}/QT$. Additionally, we used a computational biventricular model with and without a more globular ventricle structure as observed in IUGR subjects but with no wall thickness modification, where the simulated ECG and its derived intervals were measured and compared with the clinical results. The IUGR subjects showed significantly wider QRS (4 ms), longer $T_{pe}$ intervals (2 ms), and higher $T_{pe}/QT$ ratio (3%) as compared to control group. Simulations did not corroborate those findings suggesting that other cardiac remodeling different from the accounted globularity, as perhaps wall thickness, should be the responsible for the increased QRS width and $T_{pe}$ interval in IUGR, all associated with an increased transmural dispersion and a greater risk of ventricular arrhythmia.

分类号： tp3

  • 相关文献

[1]Spatial Dispersion of Activation and Repolarization Times Associated with Different Cardiac Pacing Modes. Juan Pablo Martínez,Esther Pueyo,Saúl Palacios,Radovan Smisek,Karol Curila,Uyen Nguyen,Frits W Prinzen,Josef Halamek,Filip Plesinger,Pavel Jurak. 2023

[2]A Multilayer CNN Using the ECG, Age and Sex Predicts Ventricular Arrhythmias in the General Population. Julia Ramírez,Antonio Miguel,Stefan van Duijvenboden,Michele Orini,William J Young,Andrew Tinker,Pier D Lambiase,Patricia B Munroe,Juan Pablo Martínez. 2023

[3]Coverage of PPG-Based Wearable Devices in Office Tasks. Francesco Ferrati,Eduardo Gil,Jesús Lázaro. 2023

[4]ECG Morphology-Based Markers for Risk Stratification in Hypertrophic Cardiomyopathy. Inés Noguero-Soler,Javier Ramos-Maqueda,Pablo Revilla-Martí,Esther Pueyo,Ana Mincholé. 2023

[5]Left Bundle Branch Area Pacing Generates More Physiological Ventricular Activation Sequences than Right Ventricular Pacing. Clara Sales,Ana Mincholé,Jorge Melero-Polo,Mercedes Cabrera-Ramos,Isabel Montilla-Padilla,Laura Sorinas,Ines Julián,Esther Pueyo,Javier Ramos. 2023

[6]ECG-Based Characterization of Acute Ischemia During Percutaneous Coronary Intervention. Jimena Rodríguez-Carbó,Ana Mincholé,Esther Pueyo. 2023

[7]Physiological Variations in CX43 and Fibrosis Deposition Affect Human Ventricular Electrophysiology Promoting Arrhythmia. Laura García-Mendívil,María Pérez-Zabalza,Ricardo M Rosales,José M Vallejo-Gil,Javier Fa?anás-Mastral,Manuel Vázquez-Sancho,Javier A Bellido-Morales,Alexánder S Vaca-Nú?ez,Carlos Ballester-Cuenca,Laura Ordovás,Esther Pueyo. 2023

[8]An in Silico Investigation Into The Role of SK Channels in Failing Ventricular Myocytes. Marta Gomez,Jesus Carro,Esther Pueyo,Violeta Monasterio. 2022

[9]Accelerating Stabilization of Whole-heart Models after Changes in Cycle Length. Hassaan A Bukhari,Carlos Sánchez,Esther Pueyo,Mark Potse. 2022

[10]Inter-individual Differences in Cell Composition across the Ventricular Wall May Explain Variability in ECG Response to Serum Potassium and Calcium Variations. Hassaan A Bukhari,Carlos Sánchez,Pablo Laguna,Mark Potse,Esther Pueyo. 2022

[11]Immobilisation of acid pectinase on graphene oxide nanosheets. Liu, Yang,Li, Qiang,Feng, Yuan-Yuan,Ji, Geng-Sheng,Li, Tian-Cheng,Tu, Jie,Gu, Xu-Ding,Li, Qiang.

[12]Inhibition and recovery of biomarkers of earthworm Eisenia fetida after exposure to thiacloprid. Zhang, Lan,Zhang, Yanning,Zhang, Pei,Jiang, Hongyun.

[13]Effects of heat stress on serum insulin, adipokines, AMP-activated protein kinase, and heat shock signal molecules in dairy cows. Min, Li,Shi, Bao-lu,Zheng, Nan,Wang, Jia-qi,Min, Li,Yang, Hong-jian,Cheng, Jian-bo. 2015

[14]Isobaric Tags for Relative and Absolute Quantification (iTRAQ)-Based Untargeted Quantitative Proteomic Approach To Identify Change of the Plasma Proteins by Salbutamol Abuse in Beef Cattle. Zhang, Kai,Tang, Chaohua,Liang, Xiaowei,Zhao, Qingyu,Zhang, Junmin,Zhang, Kai,Tang, Chaohua,Liang, Xiaowei,Zhao, Qingyu,Zhang, Junmin. 2018

[15]Deep sequencing-based identification of pathogen-specific microRNAs in the plasma of rabbits infected with Schistosoma japonicum. Cheng, Guofeng,Luo, Rong,Hu, Chao,Cao, Jie,Jin, Youxin. 2013

[16]Role of microRNAs in schistosomes and schistosomiasis. Zhu, Lihui,Liu, Jinming,Cheng, Guofeng. 2014

[17]New Analytical Tool for the Detection of Ractopamine Abuse in Goat Skeletal Muscle by Potential Gene Expression Biomarkers. Zhao, Luyao,Yang, Shuming,Zhang, Yanhua,Zhang, Ying,Hou, Can,Cheng, Yongyou,You, Xinyong,Tarique, Tunio Muhammad,Gu, Xu,Zhao, Zhen.

[18]Circulating miRNAs: Roles in cancer diagnosis, prognosis and therapy. Cheng, Guofeng.

[19]Metabolomics analysis reveals that bile acids and phospholipids contribute to variable responses to low-temperature-induced ascites syndrome. Shen, Yiru,Shi, Shourong,Tong, Haibing,Zou, Jianmin,Shi, Shourong,Guo, Yuming.

[20]The Reference Dose for Subchronic Exposure of Pigs to Cadmium Leading to Early Renal Damage by Benchmark Dose Method. Wu, Xiaosheng,Wei, Shuai,Wei, Yimin,Guo, Boli,Zhao, Duoyong,Liu, Xiaoling,Cai, Xianfeng,Wu, Xiaosheng,Yang, Mingqi. 2012

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台