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Changes in Ventricular Repolarization After Right Ventricular and Left Bundle Branch Pacing

文献类型： 会议论文

第一作者： Saúl Palacios

作者： Saúl Palacios 1 ; Clara Sales 1 ; Jorge Melero 2 ; Mercedes Cabrera 2 ; Javier Ramos 2 ; Ana Mincholé 1 ; Esther Pueyo 3 ; Juan Pablo Martínez 3 ;

作者机构： 1.Aragón Institute of Engineering Research, IIS Aragón, Universidad de Zaragoza, Spain

2.Department of Cardiology, Arrhythmias Unit, Hospital Clínico Lozano Blesa, IIS Aragón, Zaragoza, Spain

3.Aragón Institute of Engineering Research, IIS Aragón, Universidad de Zaragoza, Spain|CIBER de Bioingeniería, Biomateriales y Nanomedicina Instituto de Salud Carlos III, Spain

关键词： Pacemakers;Modulation;Europe;Synchronization;Oscillators

会议名称： [ "Conference of The European Study Group on Cardiovascular Oscillations" , "Conference of the European Study Group on Cardiovascular Oscillations"]

主办单位：

页码： 1-2

摘要： Left bundle branch pacing (LBBP) has recently emerged as an alternative to the widely used right ventricular pacing (RVP), which presents limitations related to the induced ventricular activation dyssynchrony. Here, we measured the QRS complex duration (QRSd) and an index of sympathetic modulation of ventricular repolarization, called Periodic Repolarization Dynamics (PRD), one day and one year after pacemaker implantation. In our cohort of patients with right and left bundle branch block, LBBP induced a decrease in QRSd (median [IQR] at baseline: $mathbf{1 6 0. 5}$ [20.20] ms, after one day: 133.5 [25.25], after one year: $133[23.8] mathrm{ms}$), thus indicating higher activation synchronization. On the other hand, RVP showed no significant changes (155.0 [15.15], 156. 5 [30.30] and 150.5 [34.34] ms). PRD was reduced after one-day pacing for both LBBP and RVP, but returned to baseline values after one year. In conclusion, LBBP shows improved activation synchronization as compared to RVP, with no significant differences in sympathetically-mediated repolarization oscillations between the two pacing techniques.

分类号： r322.1

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