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Evaluation of a QT Adaptation Time Estimator for ECG Exercise Stress Test in Controlled Simulation

文献类型： 会议论文

第一作者： Cristina Pérez

作者： Cristina Pérez 1 ; Esther Pueyo 2 ; Juan Pablo Martínez 2 ; Leif S?rnmo 3 ; Pablo Laguna 2 ;

作者机构： 1.BSICoS Group, I3A IIS Aragón, University of Zaragoza, Zaragoza, Spain

2.BSICoS Group, I3A IIS Aragón, University of Zaragoza, Zaragoza, Spain|CIBER-Bioengineering, Biomaterials and Nanomedicine (CIBER BBN), Madrid, Spain

3.Department of Biomedical Engineering, Lund University, Sweden

关键词： Heart rate;Adaptation models;Electrocardiography;Robustness;Recording;Stress;Standards

会议名称： Computing in Cardiology Conference

主办单位：

页码： 1-4

摘要： Slowed adaptation of the QT interval to sudden abrupt heart rate (HR) changes has been identified as a marker of ventricular arrhythmic risk. However, abrupt HR changes are difficult to induce in patients. Quantifying the QT adaptation time in gradual HR changes, as observed in ECGs recording during an exercise stress test, has been recently proposed. The time lag between the QT series and an instantaneous memoryless HR-dependent QT series along stress test was computed as QT memory. Here, this method was evaluated in a control scenario using simulated exercise stress test ECG signals presenting different QT adaptation times. The method robustness was studied by contaminating the ECGs with muscular noise (MN) signals with different Signal-to-Noise ratio (SNR) values, either synthetic or extracted from real recordings. We found that delineation of the T-wave end point in the first transformed lead from Periodic Component Analysis offers the best performance for low SNR. Moreover, we confirmed that the estimator provides an unbiased estimate of the QT memory introduced in the simulations for the studied range of SNR values (25 to 50 dB).

分类号： tp3

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