Tissue Response and Degradation of Novel Gelatin-Based Biomaterials in vivo: Insights from Small Animal Multimodal Imaging
文献类型： 会议论文
第一作者： Christoph Tondera
作者： Christoph Tondera 1 ; Sandra Ullm 1 ; Sebastian Meister 1 ; Tim P. Gebauer 2 ; Axel T. Neffe 2 ; Andreas Lendlein 2 ; Jens Pietzsch 1 ;
作者机构： 1.Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology, Dresden, Germany
2.Institute of Biomaterial Science and Berlin-Brandenburg Centre for Regenerative Therapies, Helmholtz-Zentrum Geesthacht, Teltow, Germany
会议名称： European Conference on Biomaterials
主办单位：
页码： 183-
摘要： This multimodal imaging study revealed that the crosslinking level of gelatin-based biomaterials determines the degradation time of the material. This allows for targeted modification of the material according to the respective tissue that needs to be replaced. Furthermore, except for minor pro-inflammatory reactions at the incision site, no adverse tissue response could be observed during and after the degradation which is consistent with good biocompatibility of these novel materials.
分类号： Q691
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