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Pro-inflammatory Response to Novel Gelatin-based Biomaterials with Tailorable Mechanical Properties in vitro

文献类型: 会议论文

第一作者: Sandra Ullm

作者: Sandra Ullm 1 ; Anne Krueger 2 ; Tim P. Gebauer 2 ; Axel T. Neffe 2 ; Christoph Tondera 1 ; Andreas Lendlein 2 ; Friedrich Jung 2 ; Jens Pietzsch 1 ;

作者机构: 1.Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Department of Radiopharmaceutical and Chemical Biology, Dresden, Germany

2.Institute of Biomaterial Science and Berlin-Brandenburg Centre for Regenerative Therapies, Helmholtz-Zentrum Geesthacht, Teltow, Germany

会议名称: European Conference on Biomaterials

主办单位:

页码: 171-

摘要: These results point out that direct contact between cells and the hydrogels investigated, but not contact to their hydrolytic or enzymatic degradation products, induced inflammatory reactions in the cells. This indicates an impact of the material surface structure. In general, the materials did not induce endothelial cell dysfunction, whereas macrophages showed inflammatory activation.

分类号: Q691

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