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Gelatin/hydroxyapatite multicomponent system with a modulate biological signals

文献类型: 会议论文

第一作者: Daniela Giugliano

作者: Daniela Giugliano 1 ; Maria Grazia Raucci 1 ; Luigi Ambrosio 1 ;

作者机构: 1.Institute of Polymers, Composites and Biomaterials - National Research Council of Italy. Mostra d'Oltremare Pad.20 - Viale Kennedy 54, 80125 - Naples, Italy

会议名称: European Conference on Biomaterials

主办单位:

页码: 868-

摘要: This work demonstrated that, by an opportune GEL/HA ratio, is possible to create an HA gradient into the scaffold section, as confirmed by morphological, thermal and chemo-physical investigations. Thermal and mechanical analyses show that in GEL/HA scaffold, success of crosslinking by EDC depend on number of carboxyl group, ontent in polymer typology, and inorganic phase amount. Biological test performed by hMSC demonstrates that the materials have a good biocompatibility and support osteogenic/chondrogenic differentiation.

分类号: Q691

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