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Gene Expression Profile of Osteoblast-Like Cells on Calcium Phosphate Biomaterials

文献类型: 会议论文

第一作者: Taro Takemura

作者: Taro Takemura 1 ; Hongsong Fan 2 ; Toshiyuki lkoma 3 ; Junzo Tanaka; Nobutaka Hanagata;

作者机构: 1.Biomaterials Center, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan

2.Engineering Research Center in Biomaterials, Sichuan University, Biomaterials Building, 29# Wangjiang Road, Chengdu 610064, China

3.Department o

关键词: hydroxyapatite;tricalcium phosphate;biphasic calcium phosphate;osteoblast;gene expression;DNA microarray

会议名称: Bioceramics vol.19 pt.2

主办单位:

页码: 1087,1090-

摘要: Gene expression profile of osteoblast-like cells cultured on dense disk materials and porous materials of calcium phosphate ceramics was constructed from DNA microarray analyses. The profile revealed that gene expression patterns of porous materials were significantly different from those of dense disk materials. The porous materials had a capacity to induce expressions of genes involved in osteoblast differentiation, while dense disk materials regulated gene expressions related to osteoclastogenesis.

分类号: [ "R318.08" , "R318.08"]

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