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Development of in situ-formed interconnected porous scaffolds with low porosity

文献类型: 会议论文

第一作者: Yulin Li

作者: Yulin Li 1 ; Masanori Kikuchi;

作者机构: 1.Biomaterials Center, National Institute for Materials Science 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan

关键词: regenerative medicine;sodium carboxymethyl cellulose;polymethyl methacrylate;poly(L-lactide-co-glycolide-co-e-caprolactone);aqueous fiber;porosity

会议名称: International Symposium on Ceramics in Medicine;International Society for Ceramics Annual Meeting; 20071024-26;20071024-26; Nantes(FR);Nantes(FR)

主办单位:

页码: 415,418-

摘要: Biocompatible and water-soluble fibers (sodium carboxymethyl cellulose (CMC)) were fabricated via a wet-spinning method. The CMC fibers/ polymethyl methacrylate (PMMA) mixtures and CMC fibers/Poly (L-lactide-co-glycolide-co-e-caprolactone) (PLGC) mixtures were prepared by a heat-kneading method. For CMC fibers/PMMA, after removal of the CMC fibers from the mixtures, the interconnected porous scaffolds with porosity from 27.79 % to 60.98 % (volume percent) were obtained. For CMC fibers/PLGC, the interconnected porous scaffolds with porosity 38.55 % and 76.83 % (volume percent) were prepared. The solid CMC fibers/PLGC mixtures had the higher ultimate tensile strength and Young' s modulus than those of porous PLGC scaffolds.

分类号: [ "R318.08" , "R318.08"]

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