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Enhancement of integrin-mediated cell attachment by pre-adsorbed model proteins on poly(NaSS)-functionalized Ti6Al4V susbstrates: a QCM-D study

文献类型: 会议论文

第一作者: Helena Felgueiras

作者: Helena Felgueiras 1 ; Sven Sommerfeld 2 ; N. Sanjeeva Murthy 2 ; Joachim Kohn 2 ; Veronique Migonney 1 ;

作者机构: 1.Laboratory of Biomaterials and Specialty Polymers, LBPS-CSPBAT CNRS UMR 7244, Institut Galilee, Universite Paris XIII, 93430 Villetaneuse, France

2.New Jersey Center for Biomaterials, Rutgers University, 145 Bevier Road, Piscataway, New Jersey 08854, USA

会议名称: European Conference on Biomaterials

主办单位:

页码: 592-

摘要: Presence of sulfonate groups favored protein adsorption and cell attachment. On these altered surfaces, integrin-mediated attachment was predominant and played a major role in cell cytoskeleton organization. Poly(NaSS) was also found to have a large influence on Fn protein conformation, exposing more active binding sites.

分类号: Q691

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