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Patient-Customizable Scaffolds with Nano/Microenvironments Rich in Human Platelet's Lysate and Marine-Origin Polysaccharides for Bone Formation Induction

文献类型: 会议论文

第一作者: Sara M. Oliveira

作者: Sara M. Oliveira 1 ; Rui L. Reis 1 ; Joao F. Mano 1 ;

作者机构: 1.3B's Research Group - Biomaterials, Biodegradables and Biomimetics, AvePark, Zona Industrial da Gandra S. Claudio do Barco, 4806-909 Caldas das Taipas, Guimaraes, Portugal

会议名称: European Conference on Biomaterials

主办单位:

页码: 330-

摘要: The developed methodology allows the preparation of 3D scaffolds with multi-level tunable nano- and microenvironments that highly affect cell fate. The structuring method has shown to be effective for the introduction and stabilization of osteoinductive factors derived from hPL. By playing with the structuring parameters, the density of the hPL presented to cells, the profile and even the spatial-temporal release, highly bioactive 3D tissue engineered bone constructs can be created.

分类号: Q691

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