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Design and Characterization of Synthetic Biodegradable Films for Soft Tissue Engineering

文献类型： 会议论文

第一作者： Sofia Ribeiro

作者： Sofia Ribeiro 1 ; Emanuel M. Fernandes 2 ; Manuela E. Gomes 2 ; Rui L. Reis 2 ; Yves Bayon 1 ; Dimitrios I. Zeugolis 3 ;

作者机构： 1.Institute Medtronic, Sofradim Production

2.B's Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine

3.Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), National University of Ireland Galway (NUI Galway)

会议名称： International Joint Conference on Biomedical Engineering Systems and Technologies

主办单位：

页码： 28-32

摘要： 1 RESEARCH PROBLEM To repair soft tissue, it is vital to ensure that the biomaterial is able to mimic the complex elasticity and topography of the native tissue. Huge efforts have been invested into the development and design of appropriate elastomeric biomaterials to match the tissue of choice. However most of past studies have used non-degradable polymers as substrates. In order to obtain an optimal tissue engineered approach it is vital to study the effect of biodegradable polymers. The goal of the present study is to characterize extensively a set of biodegradable polymeric micro-grooved films and to assess its effect on cell adhesion, morphology and phenotype through optimal substrate rigidities.

分类号： R318-53

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