An overview of natural herbal extracts and compounds for combating porcine epidemic diarrhea virus
文献类型： 外文期刊
作者： Wang, Liyan 1 ; Bo, Zongyi 3 ; Sun, Liumei 1 ;
作者机构： 1.Jiangsu Univ Sci & Technol, Sch Biotechnol, Jiangsu Key Lab Sericultural & Anim Biotechnol, Zhenjiang, Peoples R China
2.Chinese Acad Agr Sci, Sericultural Sci Res Ctr, Key Lab Silkworm & Mulberry Genet Improvement, Minist Agr & Rural Affairs, Zhenjiang, Peoples R China
3.Yangzhou Univ, Joint Int Res Lab Agr & Agriprod Safety, Minist Educ China, Yangzhou, Peoples R China
4.Yangzhou Univ, Coll Vet Med, Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Peoples R China
关键词： porcine epidemic diarrhea virus; natural herbal products; antiviral; single-herb extracts; compound herbal formulations
期刊名称：FRONTIERS IN VETERINARY SCIENCE （ 影响因子：2.9； 五年影响因子：3.3 ）
ISSN：
年卷期： 2025 年 12 卷
页码：
收录情况： SCI
摘要： Porcine epidemic diarrhea virus (PEDV) is the etiological agent responsible for the acute infectious intestinal disease known as porcine epidemic diarrhea (PED), which results in severe diarrhea in piglets and causes substantial economic losses to the global swine industry. Currently, no specific therapeutic agent is available for the clinical treatment of PEDV, highlighting the urgent need to screen antiviral compounds and investigate antiviral mechanisms to develop effective antiviral therapies. Using active natural ingredients in animal husbandry represents a significant contemporary trend. Natural herbal products offer numerous advantages, including abundant availability, diverse biological activities, and low toxicity and side effects, as well as a reduced likelihood of developing drug resistance. These attributes position them as valuable resources for the development of effective anti-PEDV drugs. This paper provides a comprehensive review of the current research on the inhibitory effects of herbal monomers (isolated compounds), single-herb extracts, and compound herbal formulations (derived from research) against PEDV. The aim is to establish a theoretical foundation for the screening and development of therapeutic and prophylactic agents targeting PEDV.
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