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Near telomere-to-telomere genome of the model plant Physcomitrium patens

文献类型: 外文期刊

作者: Bi, Guiqi 1 ; Zhao, Shijun 2 ; Yao, Jiawei 1 ; Wang, Huan 1 ; Zhao, Mengkai 6 ; Sun, Yuanyuan 4 ; Hou, Xueren 4 ; Haas, Fabian B. 8 ; Varshney, Deepti 9 ; Prigge, Michael 10 ; Rensing, Stefan A. 9 ; Jiao, Yuling 7 ; Ma, Yingxin 2 ; Yan, Jianbin 1 ; Dai, Junbiao 1 ;

作者机构: 1.Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Minist Agr & Rural Affairs, Key Lab Synthet Biol,Shenzhen Branch,Guangdong Lab, Shenzhen, Peoples R China

2.Chinese Acad Sci, Shenzhen Inst Synthet Biol, Shenzhen Inst Adv Technol, CAS Key Lab Quantitat Engn Biol,Guangdong Prov Key, Shenzhen, Peoples R China

3.Chinese Acad Sci, Shenzhen Inst Synthet Biol, Shenzhen Inst Adv Technol, Shenzhen Key Lab Synthet Genom, Shenzhen, Peoples R China

4.Univ Chinese Acad Sci, Beijing, Peoples R China

5.South China Agr Univ, Integrat Microbiol Res Ctr, Guangdong Prov Key Lab Microbial Signals & Dis Con, Guangzhou, Peoples R China

6.Shenzhen Univ, Coll Life Sci & Oceanog, Shenzhen, Peoples R China

7.Chinese Acad Sci, Innovat Acad Seed Design, Inst Genet & Dev Biol, State Key Lab Plant Genom, Beijing, Peoples R China

8.Max Planck Inst Biol Tubingen, Dept Algal Dev & Evolut, Tubingen, Germany

9.Univ Freiburg, Fac Chem & Pharm, Freiburg, Germany

10.Univ Calif San Diego, Dept Cell & Dev Biol, La Jolla, CA USA

11.Peking Univ, Ctr Quantitat Biol, Sch Life Sci, Beijing, Peoples R China

12.Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing, Peoples R China

期刊名称:NATURE PLANTS ( 影响因子:18.0; 五年影响因子:18.6 )

ISSN: 2055-026X

年卷期: 2024 年 10 卷 2 期

页码:

收录情况: SCI

摘要: The model plant Physcomitrium patens has played a pivotal role in enhancing our comprehension of plant evolution and development. However, the current genome harbours numerous regions that remain unfinished and erroneous. To address these issues, we generated an assembly using Oxford Nanopore reads and Hi-C mapping. The assembly incorporates telomeric and centromeric regions, thereby establishing it as a near telomere-to-telomere genome except a region in chromosome 1 that is not fully assembled due to its highly repetitive nature. This near telomere-to-telomere genome resolves the chromosome number at 26 and provides a gap-free genome assembly as well as updated gene models to aid future studies using this model organism.

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