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The soybean lecithin-cyclodextrin-vitamin E complex nanoparticles stabilized Pickering emulsions for the delivery of 8-carotene: Physicochemical properties and in vitro digestion

文献类型： 外文期刊

作者： Hao, Lei 1 ; Li, Junjiao 2 ; Mao, Jin 3 ; Zhou, Qi 3 ; Deng, Qianchun 3 ; Chai, Zhaofei 4 ; Zheng, Lei 1 ; Shi, Jie 1 ;

作者机构： 1.Hefei Univ Technol, Engn Res Ctr Bioproc, Minist Educ, Sch Food & Biol Engn, Hefei 230009, Peoples R China

2.Hubei Univ Technol, Minist Educ, Sch Biol Engn & Food, Key Lab Fermentat Engn, Wuhan 430068, Peoples R China

3.Chinese Acad Agr Sci, Minist Agr & Rural Affairs, Key Lab Biol & Genet Improvement Oil Crop, Oil Crops Res Inst,Key Lab Oilseeds Proc, Wuhan 430062, Peoples R China

4.Chinese Acad Sci, Innovat Acad Precis Measurement Sci & Technol, Wuhan Inst Phys & Math, Natl Ctr Magnet Resonance Wuhan,State Key Lab Magn, Wuhan 430071, Peoples R China

关键词： 8-Cyclodextrin; Soybean lecithin; Vitamin E; Pickering emulsion; Physical stability; Biological accessibility

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：8.2； 五年影响因子：7.8 ）

ISSN： 0141-8130

年卷期： 2024 年 265 卷

页码：

收录情况： SCI

摘要： In this work, soybean lecithin (LC) was used to modify 8-cyclodextrin (8-CD) with hydrophobic fat chains to become amphiphilic (LC-CD), and vitamin E (VE) was encapsulated in former modified 8-CD complexes (LC-CDVE), the new Pickering emulsions stabilized by LC-CD-VE and LC-CD complexes for the delivery of 8-carotene (BC) were created. The surface tension, contact angle, zeta potential, and particle size were used to assess the changes in complexes nanoparticles at various pH values. Furthermore, LC-CD-VE has more promise as Pickering emulsion stabilizer than LC-CD because of the smaller particle size (271.11 nm), proper contact angle (58.02 degrees), and lower surface tension (42.49 mN/m). The interactions between 8-cyclodextrin, soybean lecithin, and vitamin E were confirmed using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), nuclear magnetic resonance (NMR), and thermogravimetric analysis (TGA). The durability of Pickering emulsions was examined at various volume fractions of the oil phase and concentrations of nanoparticles. Compared to the emulsion stabilized by LC-CD, the one stabilized by LC-CD-VE showed superior storage stability. Moreover, for the delivery of BC, Pickering emulsions stabilized by LC-CD and LC-CD-VE can outperform bulk oil and Tween 80 stabilized emulsions in terms of UV light stability, storage stability, and bioaccessibility. This work could offer fresh perspectives on stabilizer alternatives for Pickering emulsion delivery systems.

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