您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Mof-derived hollow-open hierarchically porous carbon spheres for enzyme encapsulation and biocatalysis

文献类型： 外文期刊

作者： Zhao, Baozhu 1 ; Yang, Haowen 1 ; Mao, Jin 2 ; Shi, Jie 1 ;

作者机构： 1.Hefei Univ Technol, Engn Res Ctr Bioproc, Sch Food & Biol Engn, Minist Educ, Hefei 230009, Peoples R China

2.Chinese Acad Agr Sci, Oil Crops Res Inst, Key Lab Biol & Genet Improvement Oil Crop,Key Lab, Minist Agr & Rural Affairs, Wuhan 430062, Peoples R China

关键词： Metal-organic frameworks; Hollow hierarchical porous; ZIF-8 derived carbon; Immobilized enzymes; Biocatalysis

期刊名称：CHEMICAL ENGINEERING JOURNAL （ 影响因子：13.2； 五年影响因子：13.5 ）

ISSN： 1385-8947

年卷期： 2025 年 505 卷

页码：

收录情况： SCI

摘要： The preparation of hollow hierarchically porous Zeolitic Imidazolate Framework-8 (ZIF-8), followed by its derivation into carbon materials, emerges as an effective approach to overcome the issues of limited pore size and poor stability encountered by traditional ZIF-8 in enzyme immobilization applications. In this study, a simple and distinctive pathway was employed to fabricate spherical ZIF-8 with a hollow-open hierarchically porous structure (KHZIF-8), which was carbonized into a promising immobilized enzyme carrier, hollow-open hierarchically porous carbon spheres (C/KHZIF-8-X, where X signifies the carbonization temperature). A suite of analytical techniques was utilized to elucidate the transformation of ZIF-8 into derived carbon. Compared to ZIF8, C/KHZIF-8-X demonstrates enhanced chemical stability in aqueous systems for enzyme immobilization. C/ KHZIF-8-800, produced through optimized carbonization, achieved Candida rugosa lipase (CRL) loading of 177.4 mg g- 1 and relative activity of 81.4 %, while C/ZIF-8@CRL exhibited lower enzyme loading (66.3 mg g- 1 ), and the relative activity based on unit enzyme amount decreased to 66.6 %. Furthermore, the successful encapsulation of catalase confirmed the potential of C/KHZIF-8-800 as a universal platform for biomolecule immobilization. In application, C/KHZIF-8-800@CRL catalyzed the synthesis of oleic acid sterol esters, achieving a maximum conversion rate of 80.9 %. This study shed new light on optimizing the structure and properties of ZIF-8 and developing MOF-based immobilized enzyme reactors.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台