文献类型： 外文期刊
作者： Li, Kai 1 ; Guo, Yaning 1 ; Qi, Xin 1 ; Li, Fukai 1 ; Li, Xinran 1 ; Yang, Mengrui 1 ; Zhou, Jian 1 ; Zhou, Haiwei 3 ; Liu, Gang 2 ; Li, Liang 1 ;
作者机构： 1.Chinese Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Beijing 100081, Peoples R China
2.Shanghai Inst Measurement & Testing Technol, Shanghai 201203, Peoples R China
3.Natl Inst Food & Drug Control, State Key Lab Drug Regulatory Sci, Beijing 102629, Peoples R China
关键词： Analytical chemistry; Reference materials; Molecular detection; COVID-19
期刊名称：TRAC-TRENDS IN ANALYTICAL CHEMISTRY （ 影响因子：12.0； 五年影响因子：13.2 ）
ISSN： 0165-9936
年卷期： 2025 年 189 卷
页码：
收录情况： SCI
摘要： Analytical chemistry is experiencing a growing demand for reliable and traceable results, which have significant implications for public health and food safety. The COVID-19 pandemic further underscores the need for accurate and dependable molecular diagnostics. Nucleic acid-based reference materials (NARMs) play a crucial role in ensuring the quality of results. Notably, NARMs have gained increased attention following the outbreak of COVID-19. While previous reviews introduced NARMs but overlooked their applications in different fields. Moreover, the integration of multiple methods represents a new trend in the preparation of NARMs, but these have not appeared in previous reviews. Therefore, this review delineates NARMs classification, synthesizes characterization techniques, reviews their applications in virus diagnosis, animal diseases, pathogenic microorganisms, genetic diseases and genetically modified organism detection, and provides a perspective on NARMs' development and current challenges. In-depth study of NARMs will be significant for precise molecular diagnostics in biology, agriculture and public health.
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