Advancements in delivery systems for dietary polyphenols in enhancing radioprotection effects: challenges and opportunities
文献类型： 外文期刊
作者： Lu, Yuxuan 1 ; Wang, Kai 3 ; Hu, Lin 1 ;
作者机构： 1.Soochow Univ, Collaborat Innovat Ctr Radiat Med Jiangsu Higher E, Sch Radiat Med & Protect, State Key Lab Radiat Med & Protect, Suzhou, Jiangsu, Peoples R China
2.Soochow Univ, Collaborat Innovat Ctr Radiat Med Jiangsu Higher E, Sch Radiol & Interdisciplinary Sci RAD X, Suzhou, Jiangsu, Peoples R China
3.Chinese Acad Agr Sci, Inst Apicultural Res, State Key Lab Resource Insects, Beijing, Peoples R China
期刊名称：NPJ SCIENCE OF FOOD （ 影响因子：7.8； 五年影响因子：7.0 ）
ISSN：
年卷期： 2025 年 9 卷 1 期
页码：
收录情况： SCI
摘要： Radiotherapy, a widely employed cancer treatment, often triggers diverse inflammatory responses such as radiation enteritis, pulmonary injury, pelvic inflammation, dermatitis, and osteitis. Dietary polyphenols have recently emerged as promising agents for mitigating radiation-induced inflammation. However, their clinical application faced challenges related to variable bioavailability, individual pharmacokinetics, optimal dosing, and limited clinical evidence. Current researches revealed the efficacy of bioactive small molecule polyphenols in addressing radiation-induced inflammation. In this review, along with a comprehensive examination of the etiology and categories of radiation-induced inflammatory conditions, the diversity of polyphenols and elucidating their anti-inflammatory mechanisms are explored. This study emphasizes the recent progresses in delivery systems for dietary polyphenols, aiming to enhance radioprotection effects. The optimized utilization of polyphenols, with a theoretical framework and reference guide, is of paramount relevance. Through diverse delivery mechanisms, the more effective and safer radioprotective strategies become achievable. This endeavor aspires to contribute to breakthroughs in the dietary polyphenols' application, significantly enhancing human health protection during radiotherapy. These comprehensive insights presented here also support (pre)-clinical practices in navigating the complexities of utilizing dietary polyphenols for radioprotection, fostering advancements in the field and improving patient outcomes.
- 相关文献
作者其他论文 更多>>
-
Post-anthesis water use and biomass accumulation in winter wheat under subsoiling and microsprinkler irrigation
作者：Huang, Chao;Zhang, Yanyan;Liu, Xuchen;Gao, Yang;Ma, Shoutian;Qin, Anzhen;Li, Ying;Liu, Zhandong;Huang, Chao;Zhang, Yanyan;Liu, Xuchen;Gao, Yang;Ma, Shoutian;Qin, Anzhen;Li, Ying;Liu, Zhandong;Huang, Chao;Zhang, Yanyan;Liu, Xuchen;Ma, Shoutian;Qin, Anzhen;Li, Ying;Liu, Zhandong;Huang, Chao;Zhang, Qifeng;Gao, Zile;Wu, Guanghui;Wang, Kai
关键词：Microsprinkler irrigation; Winter wheat; Water consumption characteristics; Post-anthesis biomass accumulation; Grain-filling characteristics; North China Plain
-
Macro- and micro-plastic accumulation in soils under different intensive farming systems: A case study in Quzhou county, the North China Plain
作者：Zhang, Hanyue;Wang, Kai;Liu, Xuejun;Zhang, Hanyue;Yang, Xiaomei;Ritsema, Coen J.;Geissen, Violette;Yang, Xiaomei;Cui, Jixiao;Yan, Changrong;Yan, Changrong
关键词：Macro/micro-plastics; Intensive farming systems; Plastic film; North China Plain
-
Picoxystrobin causes mitochondrial dysfunction in earthworms by interfering with complex enzyme activity and binding to the electron carrier cytochrome c protein
作者：Zhao, Wentian;Jiang, Jiazhen;Wang, Chengju;Wang, Kai;Mu, Xiyan;Yang, Yang
关键词：Picoxystrobin; Earthworm; Mitochondrial dysfunction; Environmental level; Molecular docking
-
Broflanilide induces zebrafish neurobehavioral defects by interfering with synaptic homeostasis
作者：Wang, Kai;Liu, Xiaoyu;He, Lu;Mu, Xiyan;Wang, Chengju
关键词：broflanilide; Neural behavior changes; Synaptic injury; Neural cell heterogeneous response; Zebrafish
-
Genome-wide identification of peanut ERFs and functional characterization of AhERF28 in response to salt and drought stresses
作者：Tang, Haohong;Shi, Haonan;He, Zhaojie;Ma, Xiaohu;Wang, Kai;Liu, Feng;Cheng, Shuaishuai;Sun, Jie;Zhu, Qian-Hao;Xiong, Xianpeng
关键词：
Arachis hypogaea L.;ERF ; Abiotic stress;AhERF28 ; VIGS -
Insights into the role of GhCYP and GhTPS in the gossypol biosynthesis pathway via a multiomics and functional-based approach in cotton
作者：Mehari, Teame Gereziher;Fang, Hui;Wang, Kai;Yao, Dengbing;Wang, Baohua;Skoric, Marijana;Siler, Branislav;Liu, Fang;Araya, Tesfay
关键词：cotton; gossypol; near-isogenic lines; transcriptome; target metabolomics; correlation
-
Separation and Identification of Conventional Microplastics from Farmland Soils
作者：Ren, Siyang;Wang, Kai;Zhang, Jinrui;Liu, Xiuting;Li, Jingjing;Zhu, Tong;Ren, Kaige;Liu, Xuejun;Ren, Siyang;Graf, Martine;Collins, Benjamin I.;Jones, Davey L.;Chadwick, David R.;Zhang, Jinrui;Liu, Xuejun;Zhang, Hanyue;Liu, Xiuting;Cui, Jixiao;Yan, Changrong;Sun, Yingming;Ding, Fan;Qi, Ruimin;Xu, Li;Jiang, Xiaoxu;Yan, Changrong
关键词：
