您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Epidemiology, molecular diversity and zoonotic implications of Echinococcus granulosus sensu stricto (G1) in cattle across Nigeria: Evidence of broader transmission dynamics

文献类型： 外文期刊

作者： Amuda, Tharheer Oluwashola 1 ; Morenikeji, Olajumoke Abimbola 3 ; Li, Li 1 ; Akanbi, Ibikunle Mark 5 ; Odaibo, Georgina Nijideka 4 ; Onoja, Bernard Anyebe 4 ; Wang, Li-Qun 1 ; Dai, Guo-Dong 1 ; Chen, Wei-Gang 1 ; Wu, Yao-Dong 1 ; Wu, Ke-Ke 1 ; Wu, Yixuan 1 ; Yin, Hong 1 ; Jia, Wan-Zhong 1 ; Fu, Bao-Quan 1 ; Luo, Xue-Nong 1 ; Yan, Hong-Bin 1 ;

作者机构： 1.Lanzhou Univ, Gansu Prov Res Ctr Basic Disciplines Pathogen Biol, State Key Lab Anim Dis Control & Prevent, Coll Vet Med,Key Lab Vet Parasitol Gansu Prov,Key, Lanzhou 730046, Peoples R China

2.Chinese Acad Agr Sci, Key Lab Ruminant Dis Prevent & Control West, Natl Para Reference Lab Anim Echinococcosis, Minist Agr & Rural Affairs,Lanzhou Vet Res Inst, Lanzhou 730046, Peoples R China

3.Univ Ibadan, Dept Zool, Parasitol Unit, Ibadan, Oyo, Nigeria

4.Univ Ibadan, Coll Med, Ibadan, Oyo, Nigeria

5.Secretariat Ibadan, Minist Agr & Rural Dev, Ibadan, Oyo, Nigeria

6.Yangzhou Univ, Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou 225009, Peoples R China

关键词： Echinococcus granulosus sensu lato; Cystic echinococcosis; Nigeria; Genetic diversity; Molecular epidemiology; One health

期刊名称：ACTA TROPICA （ 影响因子：2.5； 五年影响因子：2.6 ）

ISSN： 0001-706X

年卷期： 2025 年 268 卷

页码：

收录情况： SCI

摘要： Cystic echinococcosis (CE), caused by Echinococcus granulosus sensu lato, is a major zoonotic disease with significant public health and economic impacts. Despite its endemicity in Africa, molecular data on Echinococcus granulosus s.l. genotypes in Nigeria remain limited, with existing knowledge primarily derived from sparse epidemiological studies. This study presents the first nationwide molecular assessment of CE in Nigerian cattle, evaluating prevalence, genetic diversity, and risk factors. We conducted a cross-sectional study across four abattoirs to investigate the zoonotic risk of cystic echinococcosis (CE) by examining the fertility, organ distribution and molecular characterization of the hydatid cysts in cattle, genotyping by polymerase chain reaction (PCR) and sequencing of the cytochrome c oxidase subunit 1 (cox1) and NADH dehydrogenase subunit 1 (nad1) genes. Results revealed an overall CE prevalence of 2.05 %, with regional variations (highest in Abubakar Saraki [5.79 %] and Akinyele [2.59 %]). Cysts were primarily found in lungs (1.62 %) and liver (0.43 %). Molecular analysis identified E. granulosus sensu stricto (G1 genotype) as the dominant genotype, with 3 cox1 and 6 nad1 haplotypes demonstrating substantial genetic diversity. Regional differentiation suggested localized transmission linked to livestock movement. This study provides crucial epidemiological and genetic data on E. granulosus sensu stricto in Nigeria, confirming the presence of the globally dominant G1 genotype and highlighting significant genetic diversity. The findings emphasize the need for a region-specific, One Health-based approach integrating veterinary, medical, and environmental interventions to control CE. Future research should focus on expanding surveillance to other intermediate hosts and evaluating control strategies to mitigate disease transmission.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台