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The Other Side of Defensins: Review of Antiviral Activity of Defensins (Review)

文献类型: 外文期刊

作者: Tao, K. 1 ; He, C. 1 ; Zhu, Y. 1 ; Li, Z. 1 ; Shao, D. 1 ; Li, B. 1 ; Wei, J. 1 ; Qiu, Y. 1 ; Ma, Z. 1 ; Liu, K. 1 ;

作者机构: 1.Chinese Acad Agr Sci, Shanghai Vet Res Inst, Shanghai 200241, Peoples R China

期刊名称:APPLIED BIOCHEMISTRY AND MICROBIOLOGY ( 影响因子:1.1; 五年影响因子:1.1 )

ISSN: 0003-6838

年卷期: 2025 年 61 卷 4 期

页码:

收录情况: SCI

摘要: Defensins are a class of antimicrobial peptides with antiviral, antibacterial, and biomodulatory activities [1, 2]. They present the effector molecules of the innate immune system and play an important role in host defence against pathogens, including enveloped or non-enveloped viruses, fungi and bacteria [3]. Defensins play an important role in virus invasion and infection. Here, we systematically describe the antiviral effects of defensins from four aspects: polypeptide structure, distribution in animals and antiviral mechanisms and applications emphasizing the potential of defensins as antiviral drugs.

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