文献类型: 会议论文
第一作者: Hirohito Avame
作者: Hirohito Avame 1 ; Wakiko Asayama 2 ; Nobuyuki Morimoto; Kazunari Akiyoshi;
作者机构: 1.Institute of Biomaterials & Bioengineering, Tokyo Medical and Dental University, 2-3-10, Kanda-surugadai, Chiyoda-ku, Tokyo 101-0062, Japan
2.Center of Excellence Program for Frontier Research on Molecular Destruction and Reconstruction of Tooth and B
会议名称: Controlled Release Society Annual Meeting and Exposition; 20070707-11; Long Beach,CA(US)
主办单位:
页码: 361-
摘要: Interaction between nanogel of amino group-modified cholesterol-bearing pullulan and FITC-BSA was investigated by fluorescence resonance energy transfer (FRET) and by fluorescence correlation spectroscopy (FCS). CHPNH_2 nanogels efficiently bound BSA (Kd = <1 ×10~(-10) M). Enzyme activity of β-Gal inside a cell was retained after CHPNH_2 nanogel mediated-intracellular delivery.
分类号: [ "Q81" , "Q81"]
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