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RhGF-loaded Microspheres for the Treatment of Neurodegenerative Disorders

文献类型: 会议论文

第一作者: Cunxian Song

作者: Cunxian Song 1 ; Haigang Gu;

作者机构: 1.Institute of Biomedical Engineering, Chinese Academy of Medical Sciences, The Tianjin Key Laboratory of Biomaterial Research, Tianjin, 300192,China

会议名称: Controlled Release Society Annual Meeting and Exposition; 20070707-11; Long Beach,CA(US)

主办单位:

页码: 1013-1014

摘要: RhNGF-loaded PLGA microspheres (MSs) were prepared by w/o/w emulsion and solvent evaporation technique. Adding hydrophilic additives into the inner aqueous phase greatly increased protein encapsulation efficiency. Biological activity of the encapsulated rhNGF was confirmed by PC12 cell culture. The MSs maintained a sustained release of rhNGF for at least 4 weeks in vivo.

分类号: [ "Q81" , "Q81"]

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