您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Effect of Surface Electrostatic Property on Chondrogenic Differentiation of Human Mesenchymal Stem Cells

文献类型： 会议论文

第一作者： Likun Guo

作者： Likun Guo 1 ; Yujiang Fan 2 ; Naoki Kawazoe; Guoping Chen; Junzo Tanaka; Tetsuya Tateishi; Xingdong Zhang;

作者机构： 1.National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China

2.Biomaterials Center, National Institute Materials Science, Tsukuba, Japan

关键词： surface modification;chondrogenic differentiation;electrostatic property

会议名称： Bioceramics vol.19 pt.2

主办单位：

页码： 1189,1192-

摘要： In this study, three kinds of photo-reactive polymers, namely positively charged azidophenyl-derived polyallylamine (AzPhPAAm), negatively charged azidophenyl-derived poly(acrylic acid) (AzPhPAAc) and neutral azidophenyl-derived poly (ethylene glycol) (AzPhPEG), were synthesized by introduction of photo-reactive group (-N_3) into polyallylamine, poly(acrylic acid) and poly (ethylene glycol), respectively. The structure of the azidophenyl-derived polymers was confirmed by ~1H-NMR measurement. All of the photo-reactive polymers can be pattern-grafted on the surface of cells culture plate, which was confirmed by the optical microscopy observation. The contact angle decreased after surface modification by the photo-reactive polymers. Human mesenchymal stem cells (MSC) cultured on the modified surfaces showed different morphology. The cells adhered and spread more on the PAAm- and PAAc-grafted surfaces than on the PEG-grafted surface. The pellets formed on PAAm- and PEG-grafted surfaces in condrogenic differentiation medium were positively stained by safranin O/ fast green. But the pellet formed on PAAc-grafted surface did not show obviously positive staining for safranin O/ fast green. These results indicate that the PAAm- and PEG-grafted surfaces promoted chondrogenic differentiation of MSC.

分类号： [ "R318.08" , "R318.08"]

  • 相关文献

[1]Evaluation of RGD-grafted Porous PLLA Scaffold for Chondrogenic Differentiation of Stem Cells. Hyun Jung Jung,Kwideok Park,Kyoung Jin Cho,Kwang-Duk Ann,Dong-June Ann,Dong Keun Han. 2007

[2]Chloride ions promoted the catalytic wet peroxide oxidation of phenol over clay-based catalysts. Zhou, Shiwei,Xu, Minggang,Zhang, Changbo,Song, Zhengguo,Xu, Rui,Gu, Chuantao.

[3]Study on the performance of ramie fiber modified with ethylenediamine. Liu, Zhao-Tie,Yang, Yani,Zhang, Lili,Sun, Ping,Liu, Zhong-Wen,Lu, Jian,Xiong, Heping,Peng, Yuande,Tang, Shouwei.

[4]CARTILAGINOUS TISSUE FORMATION WITH AN ELASTIC PLCL SCAFFOLD AND HUMAN ADIPOSE TISSUE-DERIVED STROMAL CELLS. So Eun Lee,Youngmee Jung,Soo Hyun Kim,Sang-Heon Kim,Jong Won Rhie,Young Ha Kim,Byoung Goo Min. 2007

[5]Calcium Titanate Film-Coating on Titanium with Hydrothermal Treatments. Masayuki Kon,Razia Sultana,Emi Fujihara,Kenzo Asaoka,Tetsuo Ichikawa. 2007

[6]Preparation of a Bioactive Xenograft. Hyung-Sup Kim,Yong-Keun Lee,Bum-Soon Lim,Chong-Pyong Chung,Sang-Hoon Rhee. 2007

[7]Surface Modified Poly(vinyl alcohol) Nanofiber for the Artificial Corneal Stroma. Hisatoshi Kobayashi. 2007

[8]A Comparative Study of Porous Titanium with Different Surface Modification Implanted in Dogs. CY Zhao,H Li,T Yuan,HS Fan,XD Zhang,ZW Gu. 2007

[9]Electrochemical Properties of Ti-6Al-4V ELI Alloy after Anodization. Marta Kiel,Janusz Szewczenko,Jan Marciniak,Katarzyna Nowinska. 2012

[10]Synthesis of Poly(ε-caprolactone)-Organosiloxane Hybrid containing Amine Group. Sang-Hoon Rhee,Sun Ja Lee,Young Mi, Kang,Yong-Keun Lee,Bum-Soon Lim,Seung Jin Lee. 2007

[11]Anodic oxidation of titanium for implants and prosthesis: processing, characterization and potential improvement of osteointegration. J. Pavón,O. Galvis,F. Echeverría,J.G. Casta?o,M. Echeverry,S. Robledo,E. Jiménez-Piqué,A. Mestra,M. Anglada. 2013

[12]Differentiation of human bone marrow stromal cells onto gelatin cryogel scaffolds. L. Fassina,E. Saino,L. Visai,M.A. Avanzini,M.G. Cusella De Angelis,F. Benazzo,S. Van Vlierberghe,P. Dubruel,G. Magenes. 2010

[13]Blood Compatibility of Novel Zwitterionic PEG-grafted Nitinol Alloy for Peripheral Arterial Stents. Jae Hoon Kim,Jun Sik Son,Kwideok Park,Jong-Man Kim,Jae-Jin Kim,Kwang-Duk Ann,Dong Keun Han. 2007

[14]Bone-like Apatite Forming Ability on Surface Modified Chitosan Membrane in Simulated Body Fluid. SangHoon Rhee. 2003

[15]Collagenous Molecule Immobilization on Hydroxyapatite Surface. Bo Jiang,Zhihong Wu,Jingying Zeng,Jian Lu,Qingrong Wei,Xingdong Zhang,Zhongwei Gu. 2007

作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台