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Procoagulant Efficiency of Activated Hageman Factor (FXIIa) on Solid Substrates

文献类型: 会议论文

第一作者: Kaushik Chatterjee

作者: Kaushik Chatterjee 1 ; Erwin A. Vogler; Christopher A. Siedlecki; Society for Biomaterials;;

作者机构: 1.Hematology at Biomaterial Interfaces Research Group, Depts of Bioengineering, Penn State University, Hershey, PA 17033

会议名称: Society for Biomaterials Transaction of the 31st Annual Meeting vol.XXIX pt.2

主办单位:

页码: 602-

摘要: Comparison of surface-bound FXIIa procoagulant efficiency suggests that the surface properties do not affect procoagulant efficiency of the enzyme. Moreover, in contrast to other theories, repeated adsorption-desorption of the enzyme is not essential for coagulation, suggesting that the surface is necessary for activation, but not propagation of the cascade.

分类号: R318.08

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