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Mechanism of Resistance Against Erythromycin in Streptococcus Egui

文献类型： 会议论文

第一作者： LI Yan-hua

作者： LI Yan-hua 1 ; JIANG Cheng-gang; CAI Xue-hui; TONG Guang-zhi; LIU Di; TONG Heng-min; 中国科学院文献情报中心; 中国生物技术发展中心; 中国生物工程学会;;

作者机构： 1.Harbin Veterinary Research Institute of China Agricultural Academy Science( CAAS) Harbin 150001 , China

关键词： streptococcus egui erythromycin;resistance mechanism ribosome methylation

会议名称： China Biotechnology 2005 vol.25 Supplement:Research and Progress of Modern Agro-Biotechnology Proceedings of International Agro-Biotechnology Conference 2005

主办单位：

页码： 288-292

摘要： Streptococcus egui was screened for resistance against erythromycin by the disk diffusion . It showed constitutive resistance to erythromycin (cMLS phenotype). The minimum inhibitory concentration (MIC) was determined by broth microdilution. The MIC against erythromycin was determined, MIC >64 μg/ml. The ermb and the mefA/E gene were amplified by PCR assay. It was positive for the ermb gene, but negative for the mefA/E gene. A 639bp fragment of the ermb genes of Streptococcus egui was sequenced and compared with ermb genes of Streptococcus gallolyticus and Staphylococcus intermedius. A 99. 8% identity was found among them. This study demonstrated that resistance mechanism against erythromycin in Streptococcus egui was mediated by ribosome methylation, which encoded by the ermb gene.

分类号： S18

  • 相关文献

[1]Mechanism of Resistance Against Erythromycin in Streptococcus Egui. LI Yan-hua,JIANG Cheng-gang,CAI Xue-hui,TONG Guang-zhi,LIU Di,TONG Heng-min. 2005

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