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Mechanism of Resistance Against Erythromycin in Streptococcus Egui

文献类型： 会议论文

第一作者： LI Yan-hua

作者： LI Yan-hua 1 ; JIANG Cheng-gang; CAI Xue-hui; TONG Guang-zhi; LIU Di; TONG Heng-min;

作者机构： 1.Harbin Veterinary Research Institute of China Agricultural Academy Science ( CAAS) Harbin 150001, China

关键词： Streptococcus egui erythromycin;Resistance mechanism ribosome methylation

会议名称： Research and progress of modern agro-biotechnology

主办单位：

页码： 288-292

摘要： Streptococcus egui was screened for resistance against eiythromycin by the disk diffusion. It showed constitutive resistance to erythromycin (cMLS phenotype). The minimum inhibitory concentration (MIC) was determined by broth microdilution. The MIC against erythromycin was determined, MIC >64 mug/ml. The ermb and the mefA/E gene were amplified by PCR assay. It was positive for the ermb gene, but negative for the mefA/E gene. A 639bp fragment of the ermb genes of Streptococcus egui was sequenced and compared with ermb genes of Streptococcus gallolyticus and Staphylococcus intermedius. A 99. 8% identity was found among them. This study demonstrated that resistance mechanism against erythromycin in Streptococcus egui was mediated by ribosome methylation, which encoded by the ermb gene.

分类号： S188

  • 相关文献

[1]Mechanism of Resistance Against Erythromycin in Streptococcus Egui. LI Yan-hua,JIANG Cheng-gang,CAI Xue-hui,TONG Guang-zhi,LIU Di,TONG Heng-min,中国科学院文献情报中心; 中国生物技术发展中心; 中国生物工程学会;. 2005

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