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Mechanical Stabilisation of Non-Toxic Collagen Fibres for Tendon Repair

文献类型: 会议论文

第一作者: Anna Sorushanova

作者: Anna Sorushanova 1 ; India Sweeny 1 ; Abhay Pandit 1 ; Dimitrios Zeugolis 1 ;

作者机构: 1.Network of Excellence for Functional Biomaterials (NFB), National University of Ireland, Galway, Ireland

会议名称: European Conference on Biomaterials

主办单位:

页码: 924-

摘要: StarPEG crosslinking provided collagen fibres with sufficient mechanical properties and stability for use as a tendon graft substitute compared to non-cross-linked tendon fibres. In vitro assessment of tenocytes showed proliferation and alignment on StarPEG collagen fibres, indicating tenocyte function was not compromised compared to GTA and EDAC-HCL. PCR results showed expression of tenogenic markers specific to tendon. Ongoing and future in vivo work is a sheep Achilles tendon model.

分类号: Q691

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