Progress in combination vaccines and the co-administration of influenza virus and SARS-CoV-2 vaccines
文献类型： 外文期刊
作者： Hu, Chengyu 1 ; Niu, Chenguang 1 ; Li, Xiaohui 1 ; He, Ke 2 ; Li, Mengyu 2 ; Gao, Xiaonan 2 ; Wei, Qiannan 1 ; Sun, Weiyang 3 ; Zhao, Yongkun 3 ; Li, Yuanguo 3 ; Xia, Xianzhu 3 ; Ren, Zhiguang 1 ; Li, Xiaodong 1 ; Wang, Tiecheng 3 ;
作者机构： 1.Henan Univ, Affiliated Hosp 1, Henan Prov Engn Technol Res Ctr Intelligent Diag &, Sch Basic Med Sci, Kaifeng, Peoples R China
2.Henan Univ, Sch Pharm, Inst Tradit Chinese Med, Kaifeng, Peoples R China
3.Chinese Acad Agr Sci, Changchun Vet Res Inst, Changchun, Peoples R China
4.Yangzhou Univ, Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Peoples R China
关键词： SARS-CoV-2; influenza virus; coinfection; coadministration; combination vaccines
期刊名称：FRONTIERS IN IMMUNOLOGY （ 影响因子：5.9； 五年影响因子：6.8 ）
ISSN： 1664-3224
年卷期： 2025 年 16 卷
页码：
收录情况： SCI
摘要： COVID-19 and seasonal influenza have taken a huge toll on the global economy and global health. Given the potential of COVID-19 to transform into a chronic epidemic akin to seasonal influenza, the influenza virus and SARS-CoV-2 will continue to be a significant threat to healthcare for some time to come. Coinfection involving the two viruses has been proven to worsen the severity of the illness, as evidenced by clinical observational data. Vaccination remains the most effective measure in the prevention and treatment of infectious diseases. In addition, the coadministration of influenza virus and SARS-CoV-2 vaccines offered greater benefits than either vaccine alone. Combination vaccines are also a major hotspot in novel vaccine development. This review highlights the advancements in the development of combined vaccines for COVID-19 and seasonal influenza, as demonstrated in animal studies and clinical trials, and emphasizes the importance of a combined vaccine.
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