文献类型： 外文期刊

作者： Xu, Songsong ¹ ; Akhatayeva, Zhanerke ⁴ ; Liu, Jiaxin ¹ ; Feng, Xueyan ¹ ; Yu, Yi ¹ ; Badaoui, Bouabid ⁵ ; Esmailizadeh, Ali ⁶ ; Kantanen, Juha ⁷ ; Amills, Marcel ⁸ ; Lenstra, Johannes A. ¹⁰ ; Johansson, Anna M. ¹¹ ; Coltman, David W. ¹² ; Liu, George E. ¹⁴ ; Curik, Ino ¹⁵ ; Orozco-terWengel, Pablo ¹⁷ ; Paiva, Samuel R. ¹⁸ ; Zinovieva, Natalia A. ¹⁹ ; Zhang, Linwei ²⁰ ; Yang, Ji ¹ ; Liu, Zhihong ²¹ ; Wang, Yachun ¹ ; Yu, Ying ¹ ; Li, Menghua ¹ ;

作者机构： 1.China Agr Univ, Frontiers Sci Ctr Mol Design Breeding MOE, Beijing 100193, Peoples R China

2.China Agr Univ, State Key Lab Anim Biotech Breeding, Beijing 100193, Peoples R China

3.China Agr Univ, Coll Anim Sci & Technol, Beijing 100193, Peoples R China

4.Chinese Acad Agr Sci, Inst Grassland Res, Hohhot 010010, Peoples R China

5.Mohammed V Univ Rabat, Fac Sci, Dept Biol, Lab Biodivers Ecol & Genome, Rabat 10106, Morocco

6.Shahid Bahonar Univ Kerman, Dept Anim Sci, Fac Agr, Kerman 76169133, Iran

7.Nat Resources Inst Finland Luke, Prod Syst, FI-31600 Jokioinen, Finland

8.Campus Univ Autonoma Barcelona, Ctr Res Agr Genom CRAG, Dept Anim Genet, CSIC IRTA UAB UB, Bellaterra 08193, Spain

9.Univ Autonoma Barcelona, Dept Ciencia Anim & Dels Aliments, Bellaterra 08193, Spain

10.Univ Utrecht, Fac Vet Med, NL-3584 CM Utrecht, Netherlands

11.Swedish Univ Agr Sci, Fac Vet Med & Anim Sci, Dept Anim Breeding & Genet, SE-75007 Uppsala, Sweden

12.Univ Alberta, Dept Biol Sci, Edmonton, AB T6G 2E9, Canada

13.Western Univ, Dept Biol, London, ON N6A 5B7, Canada

14.USDA ARS, Anim Genom & Improvement Lab, BARC, Beltsville, MD 20705 USA

15.Univ Zagreb, Fac Agr, Dept Anim Sci, Zagreb 10000, Croatia

16.Hungarian Univ Agr & Life Sci MATE, Inst Anim Sci, H-7400 Kaposvar, Hungary

17.Cardiff Univ, Sch Biosci, Cardiff CF1 03AX, Wales

18.Embrapa Genet Resources & Biotechnol, Lab Anim Reprod, Brasilia, DF, Brazil

19.LK Ernst Fed Sci Ctr Anim Husb, Podolsk 142132, Moscow Region, Russia

20.China Japan Friendship Hosp, Dept Neurol, Beijing 100029, Peoples R China

21.Inner Mongolia Agr Univ, Coll Anim Sci, Hohhot 010018, Peoples R China

22.China Agr Univ, Sanya Inst, Sanya 572024, Peoples R China

关键词： ruminant livestock; genomics; domestication; genetic improvement

期刊名称：SCIENCE CHINA-LIFE SCIENCES （ 影响因子：9.5； 五年影响因子：8.1 ）

ISSN： 1674-7305

年卷期： 2025 年 68 卷 4 期

页码：

收录情况： SCI

摘要： Ruminant livestock provide a rich source of products, such as meat, milk, and wool, and play a critical role in global food security and nutrition. Over the past few decades, genomic studies of ruminant livestock have provided valuable insights into their domestication and the genetic basis of economically important traits, facilitating the breeding of elite varieties. In this review, we summarize the main advancements for domestic ruminants in reference genome assemblies, population genomics, and the identification of functional genes or variants for phenotypic traits. These traits include meat and carcass quality, reproduction, milk production, feed efficiency, wool and cashmere yield, horn development, tail type, coat color, environmental adaptation, and disease resistance. Functional genomic research is entering a new era with the advancements of graphical pangenomics and telomere-to-telomere (T2T) gap-free genome assembly. These advancements promise to improve our understanding of domestication and the molecular mechanisms underlying economically important traits in ruminant livestock. Finally, we provide new perspectives and future directions for genomic research on ruminant genomes. We suggest how ever-increasing multiomics datasets will facilitate future studies and molecular breeding in livestock, including the potential to uncover novel genetic mechanisms underlying phenotypic traits, to enable more accurate genomic prediction models, and to accelerate genetic improvement programs.