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Efficient One-Step Synthesis of Lactide with High Yield and Selectivity Using Brønsted Acid Catalysis

文献类型: 外文期刊

作者: Qiu, Wenqi 1 ; Liu, Yukang 1 ; Zhang, Yufei 1 ; Wang, Xiaotao 1 ; Guo, Yuman 1 ; Liu, Hui 1 ; Ouyang, Canbin 2 ; Guo, Zongxia 1 ; Zhao, Yingjie 1 ;

作者机构: 1.Qingdao Univ Sci & Technol, Engn Res Ctr High Performance Polymer & Molding Te, Minist Educ, Qingdao 266042, Peoples R China

2.Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China

关键词: biodegradable polymers; Br & oslash;nsted acid catalysts; lactide syntheses; poly-lactic acid

期刊名称:CHEMSUSCHEM ( 影响因子:6.6; 五年影响因子:7.7 )

ISSN: 1864-5631

年卷期: 2025 年 18 卷 13 期

页码:

收录情况: SCI

摘要: In this work, a one-step method synthesis of lactide is reported instead of the traditional two-step method. The selection of a suitable acid catalyst polyphosphoric acid and optimization of reaction conditions result in a yield of 97%. Moreover, this new one-step strategy eliminates the need for metal catalysts and does not require high-temperature conditions, thereby avoiding the issue of racemization. The simple one-step strategy offers a combination of efficiency, sustainability, and product quality improvements, making it a modern, practical approach to lactide synthesis.

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