Hollow Double-Layered Mesoporous Silica as an Enzyme Immobilization Platform: Enhancing Biocatalytic Efficiency in Docosahexaenoic Acid Phosphatidylcholine-Phosphatidylcholine
文献类型： 外文期刊
作者： Li, Xuefeng 1 ; Wei, Jun 2 ; Zhang, Yufei 1 ; Xu, Yuanzhi 1 ; Yuan, Wenlong 2 ; Mei, Lin 2 ; Yu, Shengjiao 2 ; Zheng, Mingming 1 ;
作者机构： 1.Chinese Acad Agr Sci, Minist Agr,Oil Crops Res Inst, Hubei Key Lab Lipid Chem & Nutr, Hubei Hongshan Lab,Key Lab Oilseeds Proc, Wuhan 430062, Peoples R China
2.Southwest Med Univ, Sch Pharm, Green Pharmaceut Technol Key Lab Luzhou City, Luzhou 646000, Sichuan, Peoples R China
3.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
关键词： immobilized enzyme; hollow double-layered structure; selective etching; bifunctionally modification; structural phospholipid
期刊名称：ACS APPLIED MATERIALS & INTERFACES （ 影响因子：8.2； 五年影响因子：8.5 ）
ISSN： 1944-8244
年卷期： 2025 年
页码：
收录情况： SCI
摘要：
This study reports the synthesis of bifunctional hollow double-layered mesoporous silica (HdlMS) nanoparticles as an effective support for enzyme catalysis. Using a self-template method combined with sol-gel processing, selective etching, and surface modification with alkyl groups and nitrogenous fatty amine groups, we successfully prepared the NH2/C8-HdlMS carrier. Phospholipase A1 was then immobilized onto this carrier to construct PLA1@NH2/C8-HdlMS, which was subsequently applied to the synthesis of docosahexaenoic-acid-enriched phosphatidylcholine. The results demonstrated a docosahexaenoic acid incorporation rate of 67% within 8 h, and a catalytic efficiency (CE) of 18.84 mmol
- 相关文献
作者其他论文 更多>>
-
Efficient One-Step Synthesis of Lactide with High Yield and Selectivity Using Brønsted Acid Catalysis
作者：Qiu, Wenqi;Liu, Yukang;Zhang, Yufei;Wang, Xiaotao;Guo, Yuman;Liu, Hui;Guo, Zongxia;Zhao, Yingjie;Ouyang, Canbin
关键词：biodegradable polymers; Br & oslash;nsted acid catalysts; lactide syntheses; poly-lactic acid
-
Broadly adapted and efficient enzymatic transesterification production of medium and long-chain triglycerides via coconut oil and long-chain triacylglycerols
作者：Yang, Chuang;Zhou, Yibin;Li, Shiyi;Zheng, Mingming;Zhang, Yufei;Xu, Yuanzhi;Zheng, Mingming
关键词：Medium- and long-chain triglycerides; Enzymatic transesterification; Hollow mesoporous silica spheres; Immobilized enzyme; Molecular docking
-
The influence of different antioxidants on the properties of diacylglycerol based oleogels
作者：Hu, Fang;Zhang, Liwen;Ding, Daoyu;Zhao, Suyuan;Long, Jialing;Zheng, Mingming;Li, Shiyi;Zheng, Mingming
关键词：Diacylglycerol oleogel; Antioxidants; Crystal structure; Oxidation stability; Synchronous lifting effect
-
The structuring mechanism and in vitro digestion of novel EPA-rich medium- and long-chain triacylglycerol oleogels
作者：Zhao, Suyuan;Zhu, Yan;Zhang, Liwen;Hu, Fang;Xu, Wei;Zheng, Mingming;Zhou, Yibin;Li, Shiyi;Zheng, Mingming
关键词：Triglyceride profiles; Oleogel; Structured lipids; EPA
-
Enzymatic synthesis and antioxidation characterization of various acylated chlorogenic acids via regioselective and recyclable immobilized lipases
作者：Song, Shuaitao;Zhang, Yi;Liu, Tieliang;Zhang, Yufei;Goh, Kheng-Lim;Zheng, Mingming
关键词：Acylated chlorogenic acids; Antioxidation stability; Enzymatic interesterification; High liposolubility; Molecular docking
-
Molecular docking simulation reveals the lipase-substrate binding mechanism in the enzymatic synthesis of diacylglycerol-enriched vegetable oils
作者：Liu, Run;Zhang, Yi;Xu, Yuanzhi;Liu, Zhonghui;Chen, Jinhang;Zhang, Yufei;Zheng, Mingming;Goh, Kheng-Lim
关键词：Enzymatic glycerolysis; Immobilized lipase; High-speed homogenization; Diacylglycerol; Functional lipids
-
Functional oleogels constructed by short-and long-chain acyl triacylglycerols: Characterization and in vitro simulated digestion
作者：Hu, Fang;Zhang, Liwen;Zhu, Yan;Zhao, Suyuan;Xu, Wei;Yu, Zhenyu;Zheng, Mingming;Zhou, Yibin;Li, Shiyi;Zheng, Mingming
关键词：Functional oleogel; Short-and long-chain acyl triacylglycerols; Structured lipid; Structural properties
