您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Probiotics encapsulated by calcium pectin/chitosan-calcium pectin/sodium alginate-pectin-whey through biofilm-based microencapsulation strategy and their preventive effects on ulcerative colitis

文献类型： 外文期刊

作者： Rao, Yu 1 ; Deng, Jia 1 ; Zhang, Chengyi 1 ; Song, Yunlong 1 ; Liu, Lei 2 ;

作者机构： 1.Xihua Univ, Sch Food Sci & Bioengn, Food Microbiol Key Lab Sichuan Prov, Chengdu 610039, Peoples R China

2.Lanzhou Univ, Lanzhou Vet Res Inst, Chinese Acad Agr Sci, State Key Lab Anim Dis Control & Prevent,Coll Vet, Lanzhou 730000, Peoples R China

关键词： Biofilm-based probiotics microencapsulation; Microencapsulate characteristics; Tolerance properties; Ulcerative colitis; Gut microbiota

期刊名称：FOOD HYDROCOLLOIDS （ 影响因子：11.0； 五年影响因子：11.3 ）

ISSN： 0268-005X

年卷期： 2025 年 158 卷

页码：

收录情况： SCI

摘要： Biofilm-based probiotics have emerged as a compelling approach for administering probiotics. Selecting appropriate wall materials for enclosing probiotics in biofilm structure is viewed as an advanced method of microencapsulation. In this study, Lactiplantibacillus paraplanturm LR-1 was enclosed in three different types of wall materials to create calcium pectin beads (CPB), chitosan-calcium pectin beads (C-CPB), and sodium alginate-pectin-whey beads (SPW). The biofilm cells of LR-1 were cultured externally and then encapsulated to create CPB-ex-LR-1, ex-LR-1, C-CPB-ex-LR-1 ex-LR-1 and SPW-ex-LR-1. ex-LR-1. In contrast, LR-1 was cultured within the microcapsules to form biofilms in situ, , resulting in CPB-situ-LR-1, situ-LR-1, C-CPB-situ-LR-1 situ-LR-1 and SPW-situ-LR-1. situ-LR-1. The microcapsules displayed a relatively uniform morphology with the water contents below 10%. Nevertheless, there were noticeable edge effects in the distribution of strains within the in situ-type microcapsules. The detection of distinctive peaks unique to Lactiplantibacillus within the microcapsules confirmed the successful encapsulation. Additionally, a decrease in the intensity of the peaks linked to the wall materials indicated the formation of an amorphous structure within the microcapsules. The bacterial concentrations of situ-type microcapsules were found to surpass 10 lg CFU/g. The SPW-situ-LR-1 situ-LR-1 demonstrated superior tolerance performance, optimal release properties in simulated gastrointestinal fluids, and exceptional stability during the storage period. Additionally, SPW-situ-LR-1 situ-LR-1 showed similar effectiveness in alleviating colitis compared to fresh Biofilm-LR-1. Both Biofilm-LR-1 and SPWsitu-LR-1 pre-treatments exhibited positive effects on regulation, with SPW-situ-LR-1 situ-LR-1 administration significantly increasing the presence of Lactobacillus. . This study provides valuable insights into the development of the next- generation probiotics.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台