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Synthesis and Biological Activity of 2-Indolyl Oxazoline and Thiazoline Derivatives

文献类型： 外文期刊

作者： Liu Lei 1 ; Zheng Zhong-Bo 1 ; Qin Zhao-Hai 1 ; Fu Bin 1 ; Yuan Hui-Zhu 2 ;

作者机构： 1.China Agr Univ, Coll Sci, Beijing 100094, Peoples R China

2.Chinese Acad Agr Sci, Inst Plant Protect, Beijing 100094, Peoples R China

关键词： 2-indolyl;oxazoline;thiazoline;fungicide activity

期刊名称：CHINESE JOURNAL OF ORGANIC CHEMISTRY （ 影响因子：1.652； 五年影响因子：1.2 ）

ISSN： 0253-2786

年卷期： 2008 年 28 卷 10 期

页码：

收录情况： SCI

摘要： A series of novel 2-indolyl oxazoline and thiazoline derivatives were synthesized from 2-indolecarboxylic acid and enantiomerically amino alcohol, and characterized by IR, (1)H NMR, mass spectra and elemental analysis. There bioassays were carried out. The preliminary results showed that all the title compounds had certain fungicidal activities against 10 kinds of bacterial. Thiazolines have much better fungicidal activities than oxazolines, especially, at the concentration of 50 mg/L the inhibition ratios of 2a and 2b were up to 100% against Phytophthora parasitica Dast, Sclerotinia sclerotiorum and Phomopsis asparagi (Sacc.) Bubak.

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