文献类型： 外文期刊
作者： E, G. X. 1 ; Na, R. S. 1 ; Zhao, Y. J. 1 ; Ma, Y. H. 2 ; Huang, Y. F. 1 ;
作者机构： 1.Southwest Univ, Chongqing Engn Res Ctr Herbivores Resource Protec, Chongqing Key Lab Forage & Herbivore, Coll Anim Sci & Technol, Chongqing, Peoples R China
2.Chinese Acad Agr Sci, Inst Anim Sci, Dept Anim Genet Resources, Beijing 100193, Peoples R China
关键词： Chinese indigenous goat;Immunological diversity;Major histocompatibility complex class III;Tumor necrosis factor-alpha
期刊名称：GENETICS AND MOLECULAR RESEARCH （ 影响因子：0.764； 五年影响因子：0.912 ）
ISSN： 1676-5680
年卷期： 2015 年 14 卷 2 期
页码：
收录情况： SCI
摘要： Tumor necrosis factor-alpha is a cytokine with a wide range of effects on both lymphoid and non-lymphoid cells. In this study, we identified polymorphisms in major histocompatibility complex class III gene in the 4th exon and the 3' untranslated region of tumor necrosis factor-alpha to evaluate the immunogenetic diversity of Chinese south indigenous goat. Three single-nucleotide polymorphisms were identified and showed similar frequencies in different except MI loci. These data suggest that the high immunodiversity of the tumor necrosis factor-alpha region within these breeds can be used for strengthening variety improvement and promoting animal husbandry development in Chinese indigenous goats.
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