文献类型： 外文期刊
作者： Wen, Xiaobin 1 ; Tang, Lixin 2 ; Zhong, Ruqing 1 ; Liu, Lei 1 ; Chen, Liang 1 ; Zhang, Hongfu 1 ;
作者机构： 1.Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr, Beijing 100193, Peoples R China
2.Chinese Acad Agr Sci, Inst Special Anim & Plant Sci, State Key Lab Mol Biol Special Econ Anim, Changchun 130112, Peoples R China
关键词： ROS; oxidative stress; mitophagy; PINK1-Parkin; intestinal damage
期刊名称：ANTIOXIDANTS （ 影响因子：7.0； 五年影响因子：7.3 ）
ISSN：
年卷期： 2023 年 12 卷 2 期
页码：
收录情况： SCI
摘要： The mitochondrion is also a major site for maintaining redox homeostasis between reactive oxygen species (ROS) generation and scavenging. The quantity, quality, and functional integrity of mitochondria are crucial for regulating intracellular homeostasis and maintaining the normal physiological function of cells. The role of oxidative stress in human disease is well established, particularly in inflammatory bowel disease and gastrointestinal mucosal diseases. Oxidative stress could result from an imbalance between ROS and the antioxidative system. Mitochondria are both the main sites of production and the main target of ROS. It is a vicious cycle in which initial ROS-induced mitochondrial damage enhanced ROS production that, in turn, leads to further mitochondrial damage and eventually massive intestinal cell death. Oxidative damage can be significantly mitigated by mitophagy, which clears damaged mitochondria. In this review, we aimed to review the molecular mechanisms involved in the regulation of mitophagy and oxidative stress and their relationship in some intestinal diseases. We believe the reviews can provide new ideas and a scientific basis for researching antioxidants and preventing diseases related to oxidative damage.
- 相关文献
作者其他论文 更多>>
-
Ecological presence and functional role of bacteriophages in fermented vegetables
作者：Lin, Xia;Deng, Chunhui;Shu, Yue;Li, Shengshuai;Song, Yunlong;Kong, Hong;Liang, Ziwei;Rao, Yu;Liu, Lei
关键词：Fermented vegetables; Bacteriophages; Isolation; Microbial community
-
Probiotics encapsulated by calcium pectin/chitosan-calcium pectin/sodium alginate-pectin-whey through biofilm-based microencapsulation strategy and their preventive effects on ulcerative colitis
作者：Rao, Yu;Deng, Jia;Zhang, Chengyi;Song, Yunlong;Liu, Lei
关键词：Biofilm-based probiotics microencapsulation; Microencapsulate characteristics; Tolerance properties; Ulcerative colitis; Gut microbiota
-
Retinol metabolism signaling participates in microbiota-regulated fat deposition in obese mice
作者：Han, Hui;Yi, Bao;Zhang, Hongfu
关键词：Gut microbiota; Obesity; All-trans retinoic acid (atRA); Retinol; Adipose tissue; Fat deposition
-
Effects of maternal Escherichia coli lipopolysaccharide exposure on offspring: insights from lncRNA analysis in laying hens
作者：Yan, Zhixun;Liu, Huagui;Chu, Qin;Liu, Lei;Liu, Lei;Yu, Ying;Wang, Wei;Adetula, Adeyinka Abiola
关键词：LPS maternal stimulation; Chicken; Offspring; Egg-laying rate; lncRNA
-
Characterization of quorum quenching enzyme AiiA and its potential role in strawberry preservation
作者：Liang, Ziwei;Deng, Xi;Guo, Kaiyu;Yin, Xiaoyu;Zhang, Chengyi;Yang, Yao;Xv, Pingkang;Rao, Yu;Liu, Lei
关键词：Quorum quenching; AiiA; Chitosan; P. aeruginosa; Enterobacter sp.; Strawberry preservation
-
Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus
作者：Zhang, Shunfen;Zhong, Ruqing;Li, Kai;Wang, Huixin;Xu, Ye;Liu, Dadan;Chen, Liang;Zhang, Hongfu;Zhang, Shunfen;Lv, Huiyuan;Ma, Qiugang;Zhou, Miao
关键词：baicalin;
E. coli ; intestinal inflammation;Lactobacillus amylovorus ; macrophages polarization; TLR4 -
Screening for Bongkrekic Acid in Food Using a Monoclonal Antibody-Based Indirect Competitive Enzyme-Linked Immunosorbent Assay (icELISA)
作者：Wu, Hui-Ling;Chen, Jing;Xia, Qi-Sheng;Zhang, Shi-Wei;Chen, Xue-Jian;Feng, Rong-Hu;Zhang, Gui-Hong;Lai, Xin-Tian;Pan, Fei;Liu, Lei;Tan, Pan
关键词：Bongkrekic acid; hapten; indirect competitive enzyme-linked immunosorbent assay (icELISA); isobongkrekic acid; monoclonal antibody
