您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

New Insights into Genetic Diversity and Differentiation of 11 Buffalo Populations Using Validated SNPs for Dairy Improvement

文献类型： 外文期刊

作者： Pauciullo, Alfredo 1 ; Gaspa, Giustino 1 ; Versace, Carmine 1 ; Cosenza, Gianfranco 2 ; Piscopo, Nadia 3 ; Gu, Meichao 4 ; Coletta, Angelo 5 ; Hussain, Tanveer 6 ; Seidavi, Alireza 7 ; Nicolae, Ioana 8 ; Kovitvadhi, Attawit 9 ; Liu, Qingyou 10 ; Shang, Jianghua 11 ; Si, Jingfang 12 ; Dai, Dongmei 12 ; Zhang, Yi 12 ;

作者机构： 1.Univ Torino, Dept Agr Forest & Food Sci, I-10095 Turin, Italy

2.Univ Napoli Federico II, Dept Agr, I-80055 Naples, Italy

3.Univ Napoli Federico II, Dept Vet Med & Anim Prod, I-80137 Naples, Italy

4.Natl Inst Biol Sci, Beijing 102206, Peoples R China

5.Research Innovat & Select Buffalo, I-81100 Caserta, Italy

6.Virtual Univ Pakistan, Dept Biol Sci, Islamabad 44000, Pakistan

7.Islamic Azad Univ, Dept Anim Sci, Rasht Branch, Rasht 4147654919, Iran

8.Res & Dev Inst Bovine Breeding, Bucharest 077015, Romania

9.Kasetsart Univ, Dept Physiol, Bangkok 10900, Thailand

10.Foshan Univ, Sch Life Sci & Engn, Foshan 528225, Peoples R China

11.Chinese Acad Agr Sci, Buffalo Res Inst, Nanning 530001, Peoples R China

12.China Agr Univ, Coll Anim Sci & Technol, Beijing 100193, Peoples R China

关键词： river buffalo; swamp buffalo; wild buffalo; genetic diversity; F-ST; casein

期刊名称：GENES （ 影响因子：2.8； 五年影响因子：3.2 ）

ISSN：

年卷期： 2025 年 16 卷 4 期

页码：

收录情况： SCI

摘要： Background/Objectives: Buffalo populations exhibit distinct genetic variations influenced by domestication history, geographic distribution, and selection pressures. This study investigates the genetic structure and differentiation of 11 buffalo populations, focusing on five loci related to milk protein (CSN1S1 and CSN3) and fat metabolism (LPL, DGAT1 and SCD). The aim is to assess genetic variation between river, swamp, and wild-type buffaloes and identify key loci contributing to population differentiation. Methods: Genetic diversity was analyzed through allele frequency distribution, the Hardy-Weinberg equilibrium testing, and observed (Ho) and expected heterozygosity (He) calculations. Population structure was assessed using principal component analysis (PCA), F-ST statistics, and phylogenetic clustering (k-means and UPGMA tree). The silhouette score (SS) and the Davies-Bouldin index (DBI) were applied to determine optimal population clustering. Results: Significant genetic differentiation was observed between river and swamp buffaloes (p < 0.001). DGAT1 and CSN3 emerged as key markers distinguishing buffalo types. The Italian Mediterranean buffalo exhibited the highest genetic diversity (Ho = 0.464; He = 0.454), while the Indonesian, Chinese, and Vietnamese populations showed low heterozygosity, likely due to selection pressures and geographic isolation. The global F-ST (0.2143; p = 0.001) confirmed moderate differentiation, with closely related populations (e.g., Nepal and Pakistan) exhibiting minimal genetic divergence, while distant populations (e.g., Egypt and Indonesia) showed marked differences, and the Romanian population showed a unique genetic position. Conclusions: These findings contribute to a deeper understanding of buffalo genetic diversity and provide a valuable basis for exploiting the potential of this species in the light of future breeding and conservation strategies specific for each buffalo type.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台