Comparative transcriptome analysis of midgut of Bombyx mori under a sucrose-supplemented diet
文献类型： 外文期刊
作者： Hu, Zhenbin 1 ; Zhan, Lijie 1 ; Chen, Xinyi 1 ; Li, Jia 1 ; Zhang, Meirong 1 ; Xu, Pingzhen 1 ;
作者机构： 1.Jiangsu Univ Sci & Technol, Sch Biotechnol, Jiangsu Key Lab Sericultural & Anim Biotechnol, Zhenjiang 212100, Jiangsu, Peoples R China
2.Chinese Acad Agr Sci, Sericultural Sci Res Ctr, Key Lab Silkworm & Mulberry Genet Improvement, Minist Agr & Rural Affairs, Zhenjiang 212100, Peoples R China
关键词： Silkworm; Sucrose; Midgut; Metabolism; Transcriptome
期刊名称：SCIENTIFIC REPORTS （ 影响因子：3.9； 五年影响因子：4.3 ）
ISSN： 2045-2322
年卷期： 2025 年 15 卷 1 期
页码：
收录情况： SCI
摘要： As a monophagous insect, the silkworm possesses a restricted feeding capacity. To investigate the impact of varying sucrose concentrations on silkworm growth and development, transcriptomic analyses were conducted on the silkworm midgut. A total of 909 differentially expressed genes (DEGs) were identified, with down-regulated genes predominantly associated with starch and sucrose metabolism, fructose and mannose metabolism, galactose metabolism, and amino sugar and nucleotide sugar metabolism. These alterations suggest that excessive sucrose consumption may suppress the carbohydrate metabolism pathway in silkworm. This study offers a comprehensive analysis of transcriptomic studies on high sucrose intake in silkworm, providing insights into the effects of varying sucrose concentrations on these organisms.
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