Temperature dependence of intracellular free calcium in cardiac myocytes from rat and ground squirrel measured by confocal microscopy
文献类型： 外文期刊
第一作者： Wang, SQ
作者： Wang, SQ;Zhou, ZQ;Qian, H
作者机构：
关键词： cardiac myocyte;calcium homeostasis;hbernation
期刊名称：SCIENCE IN CHINA SERIES C-LIFE SCIENCES （ 影响因子：1.61； 五年影响因子：1.148 ）
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收录情况： SCI
摘要： The temperature-dependence of intracellular freecalcium([Ca~2+]_i)was investigated in indo-1 loaded ventricularmyoxytes from the rat, a non-hibernator, and from the groundsquirrel, a hibernator. The dissociation con- stant of indo-1 atdifferent temperature was calibrated both at pH-stat and atα-stat,and the result demonstrated that the α-stat calibration should bepreferred. Analysis of the fluorescent image showed showed a strikingincrease of[Ca~2+]_i as well as spontaneous calcium waves in ratcells, indicating an overloaded calcium.
分类号： Q1
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