文献类型: 会议论文
第一作者: Jingchao Zhang
作者: Jingchao Zhang 1 ; Juan Liao 2 ; Anchun Mo 3 ; Hongkun Wu; Yubao Li; Guoyu Lv; Xiaoyu Li;
作者机构: 1.West China College of Stomatology, Sichuan University, Chengdu, 610041, China
2.The Research Center for Nano-biomaterials, Sichuan University, Chengdu, 610046, China
3.Key Laboratory of Oral Biomedical Engineering of Ministry of Education, Chengdu, 61004
关键词: sliver;TiO_2;hydroxyapatite;nanoparticles;osteoblast
会议名称: Bioceramics vol.19 pt.1
主办单位:
页码: 447,450-
摘要: In the present in vitro study, osteoblasts proliferation, vitality and ultrastructure were investigated when cultured in the presence of silver-hydroxyapatite/titania nanoparticles (nAg-HA/TiO_2) compared to HA nanoparticles (nHA) at various concentrations and cell culture without nanoparticles for up to 120 hours. Results confirmed the detrimental influences of both nAg-HA/TiO_2 and nHA on osteoblast growth.Cell vitality was slightly higher during the earlier 24h, but after that was inhibited. Both cell proliferation and vitality by addition of nanoparticles were restricted with concentrations of nanoparticles increasing. However, the respiration rates by addition of nanoparticles were showed higher than that of the cell culture without nanoparticles. No remarkable ultrastructure changes were showed in the osteoblasts exposed nanoparticles. The difference in cell proliferation, vitality and ultrastructure between nAg-HA/TiO_2 and nHA were insignificant. It was demonstrated that biocompatibility of nAg-HA/TiO_2 is almost the same as nHA.
分类号: [ "R318.08" , "R318.08"]
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