Design and Assembly of a 3D Bioprinter and Characterization of 3D Scaffolds Produced by Casting or Printing
文献类型： 会议论文
第一作者： Daniela A. C. Belmonte
作者： Daniela A. C. Belmonte 1 ; Joaquin H. Palma 1 ; Victoria B. Molina 1 ;
作者机构： 1.Laboratory of Biomaterials, Biomechanics and Bioinstrumentation (Lab3Bio), Institute of Emerging Technologies and Applied Sciences (ITECA), UNSAM, CONICET, School of Science and Technology (ECyT), San Martfn, Buenos Aires, Argentina
关键词： 3D bioprinting;tissue engineering;3D models;Creep
会议名称： Argentinian Congress of Bioengineering
主办单位：
页码： 125-134
摘要： 3D bioprinting is emerging as a promising tool in the field of regenerative medicine and tissue engineering. Its benefits include custom design, on-demand manufacture, structural complexity, low cost, and efficiency. This work focused on converting a standard 3D printer into a 3D bioprinter and assessing the mechanical properties of the printed scaffolds. The material deposition rate was calibrated by adjusting the extruder; then a proportional relationship between the flow parameter and the deposited material rate was obtained. In addition, a realistic 3D model of a printed scaffold was generated using a Blender plug-in that translates the GCODE code into an STL file; this feature will allow further analysis using of finite element simulations. Regarding mechanical properties, tensile, oscillatory and creep tests were performed on the cast scaffolds; it has a tensile modulus of 0.2000 ± 0.0001 MPa. Furthermore, a continuous assessment of the dynamic modulus demonstrates that the scaffold dries. Creep-recovery tests show that the relaxation times and relaxation strength were similar when the stress was applied and when it was removed.
分类号： r318
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