Mask-Guided Data Augmentation for Multiparametric MRI Generation with a Rare Hepatocellular Carcinoma
文献类型: 会议论文
第一作者: Karen Sanchez
作者: Karen Sanchez 1 ; Carlos Hinojosa 2 ; Kevin Arias 2 ; Henry Arguello 2 ; Denis Kouamé 3 ; Olivier Meyrignac 4 ; Adrian Basarab 5 ;
作者机构: 1.HDSP Research Group, Universidad Industrial de Santander, Bucaramanga, Colombia|Univ Lyon, Université Claude Bernard Lyon 1, France
2.HDSP Research Group, Universidad Industrial de Santander, Bucaramanga, Colombia
3.IRIT, University of Toulouse CNRS 5505, Université Paul Sabatier Toulouse 3, France
4.Assistance Publique des h?pitaux de Paris, Bicêtre University Hospital, Biomaps, France
5.Univ Lyon, Université Claude Bernard Lyon 1, France
关键词: Deep learning;Image segmentation;Visualization;Magnetic resonance imaging;Image edge detection;Liver;Data augmentation
会议名称: IEEE International Symposium on Biomedical Imaging
主办单位:
页码: 1-5
摘要: Data augmentation is classically used to improve the overall performance of deep learning models. It is, however, challenging in the case of medical applications, and in particular for multiparametric datasets. For example, traditional geometric transformations used in several applications to generate synthetic images can modify in a non-realistic manner the patients’ anatomy. Therefore, dedicated image generation techniques are necessary in the medical field to, for example, mimic a given pathology in a realistic manner. This paper introduces a new data augmentation architecture that generates synthetic multiparametric (T1 arterial, T1 portal, and T2) magnetic resonance images (MRI) of massive macrotrabecular subtype hepatocellular carcinoma with their corresponding tumor masks through a generative deep learning approach. The proposed architecture creates liver tumor masks and abdominal edges used as input in a Pix2Pix network for synthetic data creation. The efficiency of the method is demonstrated by training it on a limited multiparametric dataset of MRI triplets from 89 patients with liver lesions to generate 1, 000 synthetic triplets and their corresponding liver tumor masks. The resulting Frechet Inception Distance score was 86.55. The proposed approach was among the winners of the 2021 data augmentation challenge organized by the French Society of Radiology.
分类号: tp391.4
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