Metabolomics Analysis of Metabolites in Forsythia suspense Fruit Using UPLC/ESI-Q TRAP-MS/MS
文献类型： 外文期刊
作者： Liu, Lingdi 1 ; Wen, Chunxiu 1 ; Tian, Wei 1 ; Xie, Xiaoliang 1 ; Wen, Saiqun 1 ; Jiang, Tao 1 ;
作者机构： 1.Hebei Acad Agr & Forestry Sci, Inst Cash Crops, Shijiazhuang 050051, Peoples R China
关键词： Forsythiae Fructus; traditional Chinese medicine; UPLC/ESI-Q TRAP-MS/MS; component; metabolite
期刊名称：PHYTON-INTERNATIONAL JOURNAL OF EXPERIMENTAL BOTANY （ 影响因子：1.407； 五年影响因子：0.996 ）
ISSN： 0031-9457
年卷期： 2022 年 91 卷 10 期
页码：
收录情况： SCI
摘要： Forsythiae Fructus, the fruit of Forsythia suspense is a traditional Chinese hebal medicine that has the antiviral and antioxidant effects in China. Modern analytical chemistry studies showed that the extracts of Forsythiae Fructus contain many bioactive components, such as flavonoids, lignans, phenolic acids, and terpenoids, which can be used to anti-inflammatory and treat toxicity, tonsillitis, ulcers, pharyngitis and acute nephritis. In order to study the types and quantities of metabolites in Forsythiae Fructus, we isolated, identified and analysed metabolites between two varieties of Forsythiae Fructus using UPLC/ESI-Q TRAP-MS/MS. The results showed that a total of 407 metabolites were identified in Forsythiae Fructus using UPLC/ESI-Q TRAP-MS/MS, including 21 terpenoids, 68 phenolic acids, 63 flavonoids, 43 amino acids and derivatives, 22 alkaloids, 55 lipids, 24 lignans and coumarins, 31 nucleotides and derivatives, 29 organic acids, and 51 other metabolites. Among, lignans and coumarins, terpenoids, organic acids, lipids, and phenolic acids were rich in Forsythiae Fructus, which accounted for more than 60% of the total metabolite content. Differential metabolite analysis revealed that 80 metabolites differed significantly between the two types of Forsythiae Fructus. Our results greatly enrich the Forsythiae Fructus phytochemical composition database and provide valuable information for further study of the metabolites of Forsythiae Fructus.
- 相关文献
作者其他论文 更多>>
-
Metabolomics and transcriptomics provide insights into the flavonoid biosynthesis pathway in the roots of developing Aster tataricus
作者：Jia, Kaixuan;Zhang, Xiaoling;Liu, Shuqi;Liu, Xiaoqing;Yang, Taixin;Ge, Shujun;Jia, Kaixuan;Zhang, Xiaoling;Meng, Yijiang;Liu, Shuqi;Liu, Xiaoqing;Yang, Taixin;Ge, Shujun;Meng, Yijiang;Wen, Chunxiu;Liu, Lingdi
关键词：Aster tataricus; Differentially expressed genes; Flavonoids; Metabolite; Transcriptome
-
Integrated Data Reveal the Flavonoid Biosynthesis Metabolic Pathway in Semen Ziziphi Spinosae Using Transcriptomic and Metabolomic
作者：Tian, Wei;Liu, Lingdi;Wen, Chunxiu;Jiang, Tao;Song, Zhongxing;Tang, Zhishu
关键词：Spinosin; secondary metabolites; transcriptomic; metabolomic; gene expression
-
American ginseng with different processing methods ameliorate immunosuppression induced by cyclophosphamide in mice via the MAPK signaling pathways
作者：Zhang, Yan-Ting;Lu, Yu-Shun;Li, Zhi-Man;Ren, Duo-Duo;Zhang, Yue;Sha, Ji-Yue;Huo, Xiao-Hui;Sun, Yin-Shi;Tian, Wei;Li, Shan-Shan
关键词：American ginseng; steam-processing; CTX; immunosuppression; MAPK
-
Integrating metabolomics, 16S rRNA sequencing, network pharmacology, and metorigin to explore the mechanism of Cinnamomi Cortex in treating chronic atrophic gastritis rats
作者：Liu, Yuetao;Zhang, Hui;Lu, Wentian;Liu, Yuetao;Zhang, Hui;Lu, Wentian;Jiang, Tao
关键词：Cinnamomi cortex; Chronic atrophic gastritis; Network pharmacology; Metabolomics; Metorigin; 16S rRNA sequencing
-
Genetic mapping, transcriptomic sequencing and metabolic profiling indicated a glutathione S-transferase is responsible for the red-spot-petals in Gossypium arboreum
作者：Zhang, Sujun;Cai, Xiao;Wang, Haitao;Liu, Cunjing;Tang, Liyuan;Li, Xinghe;Zhang, Xiangyun;Zhang, Jianhong;Jiang, Tao;Chen, Jie
关键词：
-
Metabolome analysis of genus Forsythia related constituents in Forsythia suspensa leaves and fruits using UPLC-ESI-QQQ-MS/MS technique
作者：Liu, Lingdi;Wen, Chunxiu;Jiang, Tao;Tian, Wei;Xie, Xiaoliang;Lu, Ruike;Feng, Jiaxing;Jin, Aihong;Wen, Saiqun;Liu, Lingdi;Wen, Chunxiu;Jiang, Tao;Tian, Wei;Xie, Xiaoliang;Lu, Ruike;Feng, Jiaxing;Jin, Aihong;Wen, Saiqun;Sun, Yu;Wei, Wei;Cui, Xusheng
关键词：
-
Integrated transcriptomic and metabolomic data reveal the flavonoid biosynthesis metabolic pathway in Perilla frutescens (L.) leaves
作者：Jiang, Tao;Liu, Lingdi;Tian, Wei;Xie, Xiaoliang;Wen, Saiqun;Wen, Chunxiu;Guo, Kunyuan
关键词：
