Fecal microbiota transplantation provides insights into the consequences of transcriptome profiles and cell energy in response to circadian misalignment of chickens
文献类型： 外文期刊
作者： Chen, Siyu 1 ; Liu, Hao 2 ; Yan, Chao 2 ; Li, Yushan 1 ; Xiao, Jinlong 2 ; Zhao, Xingbo 2 ;
作者机构： 1.Foshan Univ, Sch Life Sci & Engn, Guangdong Prov Key Lab Anim Mol Design & Precise B, Foshan 528000, Peoples R China
2.China Agr Univ, State Key Lab Anim Biotech Breeding, Beijing 100193, Peoples R China
3.Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Dept Gastroenterol, Hangzhou 310016, Zhejiang, Peoples R China
4.Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Shenzhen Branch, Guangdong Lab Lingnan Modern Agr,Genome Anal Lab M, Shenzhen 518124, Peoples R China
关键词： chicken; circadian misalignment; mitochondrion; fecal microbiota transplantation; immunity
期刊名称：POULTRY SCIENCE （ 影响因子：3.8； 五年影响因子：4.1 ）
ISSN： 0032-5791
年卷期： 2024 年 103 卷 9 期
页码：
收录情况： SCI
摘要： The circadian misalignment (CM) disordered circadian rhythms exert adverse effects on animals. Poultry as one of animals suffers health and welfare problems due to long-term lighting photoperiods caused by CM. However, the roles of CM on organ development, cell growth, metabolism and immune are still unclear in chickens. In this study, a Chinese dual-purpose native breed, was used to explore the effects of CM on transcriptomic pattern of brain and cell energy biogenesis, and further fecal microbiota transplantation (FMT) was applied to investigate its "therapy " effect from CM suffering. Our results showed that the CM led to stunting in brain and small intestine of chicken. CM decreased of cell proliferation, and energy production, mtDNA copies and expression of genes related to cell cycle or mitochondrial biogenetics, while it upregulated the reactive oxygen species (ROS) level and the sensitivity to in flammation. Interestingly, FMT rescued the organ developmental defects and cell dysfunctions induced by CM. Circadian misalignment brought about abnormal tissue and cell developments, energy biogenesis, and immune response in birds. This study provided a comprehensive perspective on understanding the regulation of CM and FMT on bird development and welfare.
- 相关文献
作者其他论文 更多>>
-
Genome-wide association study revealed candidate genes associated with leaf size in alfalfa (Medicago sativa L.)
作者：Xu, Ming;Xu, Yanchao;Liu, Hao;Yang, Qingchuan;Long, Ruicai;Chen, Lin;He, Fei;Liu, Qingsong
关键词：Alfalfa; GWAS; Leaf size; Haplotype analysis
-
Effects of Chicken Manure Combinations on Compost Maturity and Microbial Community Dynamics in Industrial-Scale Composting
作者：Wang, Weiwei;Zhang, Peng;He, Huiban;Liu, Hao;He, Haoxing;Cui, Zongjun;Yuan, Xufeng;Yuan, Xufeng;Wen, Boting;Yan, Jing
关键词：Aerobic composting; Chicken manure; Compost maturity; Microbial community
-
Climatic seasonality shapes insect community composition on the Mongolian Plateau
作者：Tang, Kuanyan;Hilal, Mian Gul;Yue, Hongru;Ding, Xiaolong;Xing, Yifang;Zhao, Jinming;Liu, Yang;Lin, Kejian;Wang, Ning;Liu, Hao;He, Zilong
关键词：Climatic seasonality; Steppe; Biodiversity; Insect community composition; PLS-PM model
-
How the impact and mechanisms of digital financial inclusion on agricultural carbon emission intensity: new evidence from a double machine learning model
作者：Zheng, Fengtian;Chen, Siyu;Wang, Xizhao
关键词：digital financial inclusion; double machine learning (DML); carbon emission intensity (CEI); impact mechanisms; green transformation
-
PIGOME: An Integrated and Comprehensive Multi-omics Database for Pig Functional Genomics Studies
作者：Han, Guohao;Yang, Peng;Li, Qiaowei;Fan, Xinhao;Chen, Ruipu;Yan, Chao;Zeng, Mu;Yang, Yalan;Tang, Zhonglin;Han, Guohao;Yang, Peng;Zhang, Yongjin;Li, Qiaowei;Fan, Xinhao;Chen, Ruipu;Yan, Chao;Zeng, Mu;Yang, Yalan;Tang, Zhonglin;Han, Guohao;Yang, Peng;Zhang, Yongjin;Li, Qiaowei;Fan, Xinhao;Chen, Ruipu;Yan, Chao;Zeng, Mu;Yang, Yalan;Tang, Zhonglin;Yang, Peng;Tang, Zhonglin;Yang, Peng;Li, Qiaowei;Zeng, Mu
关键词：Pig; Multi-omics; Genome; Gene expression; Epigenetics; Database
-
EasyMetagenome: A user-friendly and flexible pipeline for shotgun metagenomic analysis in microbiome research
作者：Bai, Defeng;Xun, Jiani;Ma, Chuang;Luo, Hao;Yang, Haifei;Hou, Huiyu;Lv, Hujie;Wan, Xiulin;Wang, Yao;Yousuf, Salsabeel;Zeng, Meiyin;Zhang, Tianyuan;Gao, Yunyun;Liu, Yong-Xin;Chen, Tong;Ma, Chuang;Yang, Haifei;Cao, Chen;Cao, Xiaofeng;Cui, Jianzhou;Deng, Yuan-Ping;Deng, Zhaochao;Yu, Hao;Zhang, Chunfang;Dong, Wenxin;Dong, Wenxue;Du, Juan;Fang, Qunkai;Fang, Wei;Fang, Yue;Luan, Yaning;Fu, Fangtian;Fu, Min;Fu, Yi-Tian;Gao, He;Ge, Jingping;Guo, Yuhao;Gong, Qinglong;Lou, Wenbo;Gu, Lunda;Yang, Li;Guo, Peng;Hai, Tang;Liu, Hao;He, Jieqiang;He, Zi-Yang;Huang, Can;Ji, Shuai;Jiang, ChangHai;Jiang, Gui-Lai;Jiang, Lingjuan;Jin, Ling N.;Li, Changchao;Kan, Yuhe;Kang, Da;Kou, Jin;Lam, Ka-Lung;Li, Chong;Li, Fuyi;Li, Liwei;Li, Miao;Li, Xin;Li, Ye;Li, Zheng-Tao;Zhu, Chengshuai;Liang, Jing;Mo, Jiayuan;Lin, Yongxin;Liu, Changzhen;Liu, Danni;Zhang, Jing;Chen, Shifu;Liu, Fengqin;Liu, Jia;Liu, Tianrui;Liu, Tingting;Wang, Xinlong;Liu, Xinyuan;Luo, Yuanyuan;Liu, Yaqun;Liu, Bangyan;Liu, Minghao;Lv, Hujie;Ma, Tengfei;Mai, Zongjiong;Niu, Dongze;Pan, Zhuo;Qi, Heyuan;Shi, Zhanyao;Song, Chunjiao;Sun, Fuxiang;Sun, Yan;Tian, Sihui;Wang, Guoliang;Wang, Hongyang;Wang, Hongyu;Wang, Huanhuan;Wang, Jing;Wang, Jun;Wang, Kang;Wang, Leli;Yao, Xiaofang;Wang, Shao-kun;Xiao, Zufei;Xing, Huichun;Xu, Yifan;Yang, Song;Yan, Shu-yan;Zhang, Yi-Bo;Yang, Yuanming;Lei, Yu;Yuan, Zhengrong;Zhang, Chunge;Zhang, Huimin;Zhang, Na;Zhang, Yupeng;Zhang, Zheng;Zhou, Mingda;Zhou, Yuanping;Zhu, Zhihao;Zhu, Lin;Zhu, Yue;Zou, Hongqin;Zuo, Anna;Dong, Wenxuan;Wen, Tao;Chen, Shifu;Chen, Shifu;Li, Guoliang
关键词：metagenome; microbiome; microbiota; pipeline; visualization
-
Comprehensive analysis of epigenetic modifications in alfalfa under cadmium stress
作者：Chen, Lin;Li, Xianyang;Liu, Hao;He, Fei;Li, Mingna;Long, Ruicai;Wang, Xue;Kang, Junmei;Yang, Qingchuan
关键词：Cadmium stress; DNA methylation; N 6 methylation; Gene expression; Alfalfa
