Ammonia and hydrogen sulfide - new insights into gut microbiota and male infertility through meta-analysis
文献类型： 外文期刊
作者： Hao, Yanan 1 ; Du, Xin 2 ; Cai, Chang 2 ; Zhao, Yong 4 ; Ren, Yonglin 2 ;
作者机构： 1.Shandong First Med Univ & Shandong Acad Med Sci, Inst Brain Sci & Brain Inspired Res, Jinan, Peoples R China
2.Murdoch Univ, Coll Environm & Life Sci, Perth, WA, Australia
3.Qingdao Agr Univ, Coll Life Sci, Qingdao, Peoples R China
4.Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr, Beijing, Peoples R China
关键词： ammonia; hydrogen sulfide; gut microbiota; male infertility; internal gases
期刊名称：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY （ 影响因子：4.8； 五年影响因子：5.5 ）
ISSN： 2235-2988
年卷期： 2025 年 14 卷
页码：
收录情况： SCI
摘要： Background: Ammonia (NH3) and hydrogen sulfide (H2S) are produced during digestion in the human gut, yet the impact of these internally generated gases on male reproduction have received limited attention in scientific research. Methods: We systematically reviewed 935 scientific publications, spanning from 1947 to 2023, focusing on external or internal NH3 and/or H2S, male infertility, and gut microbiota. Meta-analysis was conducted to evaluate the summary relative risk (RR) and 95% confidence intervals (CIs) of combined studies. Results: Our findings revealed that the internal NH3 and/or H2S were negatively related to the Lactobacillus, which is beneficial to male fertility, whereas NH3 and H2S were positively related to Bacteroides, which showed negative effects on male fertility. The meta-analysis comparing Lactobacillus and Bacteroides levels with NH3 showed statistically significant results (p<0.001). Conclusions: The meta-analysis is the first to confirm these facts and explored the potential existence of a gut microbiota-inner gases-male fertility axis in the human gut.
- 相关文献
作者其他论文 更多>>
-
Integrative multi-omics data provide insights into the biosynthesis of furanocoumarins and mechanisms regulating their accumulation in Angelica dahurica
作者：Ji, Jiaojiao;Han, Xiaoxu;Zang, Lanlan;Lin, Liqun;Hu, Donghua;Sun, Shichao;Wang, Li;Han, Xiaoxu;Ren, Yonglin;Maker, Garth;Li, Yushan;Lu, Zefu;Hu, Donghua;Wang, Li
关键词：
-
THE RELEASE OF A SMALL PERCENTAGE OF STERILE BACTROCERA DORSALIS (DIPTERA : TEPHRITIDAE) MALES RELATIVE TO FERTILE MALES INDUCES THE COLLAPSE OF THE PROGENY POPULATION
作者：Peng, Qi;Liang, Fujun;Zhu, Yanfei;Teng, Ziwen;Fan, Yinjun;Wan, Fanghao;Zhou, Hongxu;Peng, Qi;Liang, Fujun;Zhu, Yanfei;Teng, Ziwen;Fan, Yinjun;Wan, Fanghao;Zhou, Hongxu;Peng, Qi;Liang, Fujun;Zhu, Yanfei;Teng, Ziwen;Fan, Yinjun;Wan, Fanghao;Zhou, Hongxu;Lu, Yongyue;Du, Xin;Ren, Yonglin;Wan, Fanghao
关键词：Bactrocera dorsalis; Sterile insect technique; Small percentage release; Population collapse; Age-stage two-sex life table
-
Effect of different heat treatments on physicochemical properties and antioxidant characteristics of black beans
作者：Ji, Xiaolong;Zhang, Shuli;Du, Xin;Zhang, Yuning;Zhu, Yingying;Ji, Xiaolong;Zhu, Yingying;Yao, Yang
关键词：Glycine max (L.) Merr.; heat processing method; extrusion
-
Streamlined Agrobacterium rhizogenes-mediated hairy root transformation for efficient CRISPR/Cas9-based gene editing evaluation in diverse Citrullus cultivars
作者：Zhao, Yong;Zhu, Hongju;Lu, Xuqiang;Anees, Muhammad;He, Nan;Yang, Dongdong;Chen, Zihao;Liu, Wenge;Zhao, Yong;Zhang, Junhong;Hong, Zonglie;Zhu, Hongju
关键词：Citrullus lanatus; sgRNAs; Agrobacterium rhizogenes; Hairy root transformation; CRISPR/Cas9
-
The haplotype-resolved telomere-to-telomere carnation (Dianthus caryophyllus) genome reveals the correlation between genome architecture and gene expression
作者：Lan, Lan;Leng, Luhong;Liu, Weichao;Wu, Zhiqiang;Lan, Lan;Ren, Yonglin;Reeve, Wayne;Lan, Lan;Leng, Luhong;Liu, Weichao;Wu, Zhiqiang;Zhang, Xiaoni;Liu, Weichao
关键词：
-
Increased dependence on nitrogen-fixation of a native legume in competition with an invasive plant
作者：Han, Meixu;Ren, Weizheng;Zhao, Yong;Yang, Qingpei;Guo, Binglin;Han, Qinwen;Feng, Zhipei;Yang, Xitian;Kong, Deliang;Zhang, Haiyang;Liu, Mingchao;Guo, Xiaocheng;Feng, Yulong;Tang, Jinqi;Wu, Honghui;Wu, Honghui
关键词：Mycorrhizal strategy; Nitrogen depletion; Plant invasion; Root nutrient acquisition strategy; Symbiotic nitrogen fixation
-
Accumulation of Large Lineage-Specific Repeats Coincides with Sequence Acceleration and Structural Rearrangement in Plantago Plastomes
作者：Wang, Jie;Kan, Shenglong;Kong, Jiali;Nie, Liyun;Wu, Zhiqiang;Wang, Jie;Nie, Liyun;Reeve, Wayne;Wang, Jie;Ren, Yonglin;Kan, Shenglong;Fan, Weishu;Mower, Jeffrey P.;Mower, Jeffrey P.
关键词：plastid; substitution rate; inversion; repetitive DNA; inverted repeats; Plantago
