您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

The potential endocrine-disrupting of fluorinated pesticides and molecular mechanism of EDPs in cell models

文献类型： 外文期刊

作者： Liu, Yalan 1 ; Wang, Fengzhong 2 ; Li, Lin 2 ; Fan, Bei 2 ; Kong, Zhiqiang 3 ; Tan, Jianxin 1 ; Li, Minmin 2 ;

作者机构： 1.Hebei Agr Univ, Coll Food Sci & Technol, Hebei Key Lab Anal & Control Zoonot Pathogen Micro, Baoding, Peoples R China

2.Chinese Acad Agr Sci, Inst Food Sci & Technol, Key Lab Agroprod Qual & Safety Control Storage & T, State Key Lab,Lab Agroprod Qual Safety Risk Assess, Beijing 100193, Peoples R China

3.Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China

关键词： Pesticides; Endocrine-disrupting effect; Estrogen receptor; Cell models; Toxic mechanism

期刊名称：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY （ 影响因子：6.1； 五年影响因子：6.4 ）

ISSN： 0147-6513

年卷期： 2025 年 289 卷

页码：

收录情况： SCI

摘要： Environmental endocrine disruptors constitute a category of exogenous compounds that interfere with the endocrine system's functions in organisms or cells. As a class of particularly representative endocrine-disrupting chemicals, the accumulation of per- and polyfluoroalkyl substances potentially leads to adverse health effects, including hormonal disruptions, developmental issues, and cancer. However, the classification of these disruptors is intricate, and the data on their potential health risks is scattered. The research into fluorinated pesticides is somewhat superficial, with the majority of review articles in this field focusing on the structural characteristics, biodegradation processes, and environmental risks associated with these pesticides. In this study, we compared and investigated the research development processes of seven types of fluorine-containing pesticides and five types of fluorinated endocrine disruptors. The varying toxic effects of these endocrine disruptors are highly dependent on exposure conditions. Their actions are complex, affecting behavioral substances throughout the organism, and monitoring some complex biological phenotypes, sex- or age-specific effects, and behavioral learning poses significant challenges. The findings will serve as a reference for future studies on the toxicity of pesticides to humans and other organisms.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台