您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Lentinan Reduces Transmission Efficiency of COVID-19 by Changing Aerodynamic Characteristic of Exhaled SARS-CoV-2 Aerosols in Golden Hamsters

文献类型： 外文期刊

作者： Zhang, Cheng 1 ; Li, Jiaming 4 ; Cui, Huan 1 ; Jin, Yifei 4 ; Chen, Zhaoliang 1 ; Zhang, Lei 1 ; Song, Sihui 1 ; Lu, Bing 4 ; Wang, Zhongyi 4 ; Guo, Zhendong 1 ;

作者机构： 1.Chinese Acad Agr Sci, Changchun Vet Res Inst, 573 Tulip St, Changchun 130122, Peoples R China

2.State Key Lab Pathogen & Biosecur, Key Lab Jilin Prov Zoonosis Prevent & Control, 573 Tulip St, Changchun 130122, Peoples R China

3.Hebei Agr Univ, Coll Vet Med, 2596 Lucky South St, Baoding 071000, Peoples R China

4.Beijing Inst Biotechnol, 20 Dongdajie Rd, Beijing 100071, Peoples R China

关键词： lentinan; aerosol transmissibility; exhaled virus aerosols; aerodynamic diameters

期刊名称：MICROORGANISMS （ 影响因子：4.2； 五年影响因子：4.6 ）

ISSN：

年卷期： 2025 年 13 卷 3 期

页码：

收录情况： SCI

摘要： Lentinan (LNT) was found to reduce the aerosol transmission rate between golden hamsters from 100% (9/9) to 44.4% (4/9). The viral loads in the respiratory system, including the nasal turbinate, trachea, and lung, were significantly reduced in the infected golden hamsters that received LNT treatment. Furthermore, the amount of exhaled virus aerosols in hamsters treated with LNT was significantly lower than that in untreated hamsters throughout the entire disease progression. In detail, the amounts of virus-laden particles with aerodynamic diameters less than 5 mu m exhibited a significant decreasing trend following LNT treatment. Moreover, the detection rate of infectious SARS-CoV-2 in each stage of the Anderson-6 sampler exhibited a decreasing trend following LNT treatment post-infection. In summary, our findings indicate that LNT therapy represents a promising therapeutic candidate for the treatment of COVID-19 patients. Meanwhile, during the course of treatment, LNT has the potential to reduce viral infectivity in affected individuals.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台