您好，欢迎访问中国农业科学院 机构知识库！

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Effects of dietary chlorogenic acid supplementation on laying performance, egg quality, antioxidant capacity, and liver lipid metabolism in late-peak laying hens

文献类型： 外文期刊

作者： Zhao, Haitong 1 ; Guo, Lianxiang 1 ; Yan, Ming 1 ; Sun, Yue 1 ; Hong, Yan 3 ; Zhu, Mingkun 1 ;

作者机构： 1.Jiangsu Univ Sci & Technol, Sch Biotechnol, Jiangsu Key Lab Sericultural Biol & Anim Biotechno, Zhenjiang, Peoples R China

2.Chinese Acad Agr Sci, Minist Agr & Rural Affairs, Sericultural Res Inst, Key Lab Silkworm & Mulberry Genet Improvement, Zhenjiang, Peoples R China

3.Dantu Borough Agr Technol Extens Ctr, Zhenjiang,, Peoples R China

关键词： Chlorogenic acid; laying performance; antioxidant capacity; liver lipid metabolism; laying hen

期刊名称：ITALIAN JOURNAL OF ANIMAL SCIENCE （ 影响因子：2.3； 五年影响因子：2.4 ）

ISSN： 1594-4077

年卷期： 2025 年 24 卷 1 期

页码：

收录情况： SCI

摘要： This investigation focused on the effects of chlorogenic acid (CGA) on laying performance, egg quality, antioxidant capacity, and liver lipid metabolism in late-peak laying hens. Two hundred forty 43-week-old Hy-Line Brown laying hens were randomly distributed into 4 treatments receiving 0, 400, 600, and 800 mg/kg CGA for twelve weeks. Egg production rate and average egg weight were significantly elevated with 600 and 800 mg/kg CGA relative to the control group. Significant improvements were also noted in the Haugh unit, albumen height, and yolk colour in both CGA groups, along with elevated levels of ovomucin in the albumen and lutein in the yolk. CGA at 600 and 800 mg/kg doses significantly reduced serum hydrogen peroxide and malondialdehyde levels, as well as hepatic malondialdehyde levels. Meanwhile, CGA treatment significantly upregulated hepatic Nrf2 and SOD2 gene expression while downregulating Keap1 gene expression. Additionally, 600 and 800 mg/kg CGA treatment significantly decreased serum TG, T-CHO, and LDL-C levels, as well as liver TG and T-CHO levels, while increasing serum lipoprotein lipase activity. Moreover, CGA treatment significantly decreased hepatocyte lipid droplet levels, along with a notable reduction in SREBP1, FASN, ACC, and DGAT2 gene expressions, and a significant upregulation in PPAR alpha, ACOX1, and CPT1 gene expressions. Our findings demonstrate that CGA can improve laying performance, egg quality, and antioxidant capacity, and reduce liver lipid accumulation by inhibiting fatty acid synthesis and stimulating fatty acid oxidation in late-peak laying hens. A dietary supplement of 600-800 mg/kg CGA is recommended under the current experimental conditions.HIGHLIGHTSDietary supplementation CGA improved the laying performance, egg quality, and antioxidant capacity in the late-peak laying hens.CGA reduced hepatic lipid accumulation by inhibiting fatty acid synthesis and stimulating fatty acid oxidation.Under the current experimental conditions, a dietary supplemental level of 600-800 mg/kg CGA is recommended for laying hens.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台