Genome-wide association study reveals candidate genes associated with body measurement traits in Chinese Wagyu beef cattle
文献类型： 外文期刊
作者： An, B. 1 ; Xia, J. 2 ; Chang, T. 1 ; Wang, X. 1 ; Xu, L. 1 ; Zhang, L. 1 ; Gao, X. 1 ; Chen, Y. 1 ; Li, J. 1 ; Gao, H. 1 ;
作者机构： 1.Chinese Acad Agr Sci, Inst Anim Sci, Beijing 100193, Peoples R China
2.Westlake Inst Adv Study, Inst Basic Med Sci, Hangzhou 310000, Zhejiang, Peoples R China
关键词： genetic improvement; genome-wide association study; SNP Bovine HD 770K SNP array
期刊名称：ANIMAL GENETICS （ 影响因子：3.169； 五年影响因子：3.058 ）
ISSN： 0268-9146
年卷期： 2019 年 50 卷 4 期
页码：
收录情况： SCI
摘要： We performed a genome-wide association study to identify candidate genes for body measurement traits in 463 Wagyu beef cattle typed with the Illumina Bovine HD 770K SNP array. At the genome-wide level, we detected 18, five and one SNPs associated with hip height, body height and body length respectively. In total, these SNPs are within or near 11 genes, six of which (PENK, XKR4, IMPAD1, PLAG1, CCND2 and SNTG1) have been reported previously and five of which (CSMD3, LAP3, SYN3, FAM19A5 and TIMP3) are novel candidate genes that we found to be associated with body measurement traits. Further exploration of these candidate genes will facilitate genetic improvement in Chinese Wagyu beef cattle.
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