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Study on the Synthesis and Insecticidal Activity of Spinosyn A Derivatives

文献类型: 外文期刊

作者: Zhang Kai 1 ; Li Jiarong 1 ; Wen Dusu 1 ; Liu Honglin 2 ; Wang Haiyou 2 ; Lamusi, A. 2 ;

作者机构: 1.Beijing Inst Technol, Sch Chem & Chem Engn, Beijing 100081, Peoples R China

2.Chinese Acad Agr Sci, Inst Grassland Res, Hohhot 010000, Peoples R China

关键词: natural product; spinosyn A; semi-synthetic derivative; insecticidal activity

期刊名称:CHINESE JOURNAL OF ORGANIC CHEMISTRY ( 影响因子:1.652; 五年影响因子:1.2 )

ISSN: 0253-2786

年卷期: 2018 年 38 卷 12 期

页码:

收录情况: SCI

摘要: Spinosyns are a novel kind of biopesticide produced by Saccharopolyspora spinosa. Spinosyns have been widely applied in pest control because of their broad insecticidal spectrum, high insecticidal activity, low environmental impact, and low toxicity. To identify spinosyn compounds with improved insecticidal activity, a series of D-forosamine replacement derivatives of spinosyn A were synthesized. The insecticidal activities of the synthetic derivatives were evaluated against 3rd-instar larvae of Plutella xylostella. All derivatives exhibited good insecticidal activity to P. xylostella.

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