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p-Hydroxycinnamic Acids: Advancements in Synthetic Biology, Emerging Regulatory Targets in Gut Microbiota Interactions, and Implications for Animal Health

文献类型： 外文期刊

作者： Ma, Chunlai 1 ; Liang, Ziqi 1 ; Wang, Yuan 1 ; Luo, Huiying 1 ; Yang, Xiaojun 2 ; Yao, Bin 1 ; Tu, Tao 1 ;

作者机构： 1.Chinese Acad Agr Sci, Inst Anim Sci, State Key Lab Anim Nutr & Feeding, Beijing, Peoples R China

2.Northwest A&F Univ, Coll Anim Sci & Technol, Yangling, Shaanxi, Peoples R China

关键词： acids; bioactivity; animal health; gut microbiota; biosynthesis

期刊名称：JOURNAL OF NUTRITION （ 影响因子：3.8； 五年影响因子：4.2 ）

ISSN： 0022-3166

年卷期： 2025 年 155 卷 4 期

页码：

收录情况： SCI

摘要： p-hydroxycinnamic acids (p-HCAs), a class of natural phenolic acid compounds extracted from plant resources and widely distributed, feature a C6-C3 phenylpropanoid structure. Their antioxidant, anti-inflammatory, and antibacterial activities have shown great potential for applications in food and animal feed. The interactions between p-HCAs and the gut microbiota, as well as their subsequent effects on animal health, have increasingly attracted the attention of researchers. In the context of a greener and safer future, the progress and innovation in biosynthetic technology have occupied a central position in ensuring the safety of food and feed. This review emphasizes the complex mechanisms underlying the interactions between p-HCAs and the gut microbiota, providing a solid explanation for the remarkable bioactivities of p-HCAs and their subsequent impact on animal health. Furthermore, it explores the advancements in the synthetic biology of p-HCAs. This review could aid in a basis for better understanding the underlying interactions between p-HCAs and gut microbiota and animal health.

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